103878-43-9 - Names and Identifiers
103878-43-9 - Physico-chemical Properties
Molecular Formula | C8H11N3O
|
Molar Mass | 165.19 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD05022406 |
103878-43-9 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
103878-43-9 - Introduction
Pyridine-2-carboxylic acid (2-amino-ethyl)-amide, also known as Pyridine-2-carboxylic acid (2-amino-ethyl)-amide, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White or off-white crystalline solid.
-Solubility: Soluble in water and many organic solvents, such as alcohols and ketones.
-Melting point: about 150-152 ℃.
-Molecular formula: C8H11N3O.
-Molecular weight: 165.19g/mol.
Use:
-Pharmaceutical and chemical industry: Pyridine-2-carboxylic acid (2-amino-ethyl)-amide is an important intermediate compound, which can be used to synthesize drugs, pesticides and dyes. It is commonly used in the pharmaceutical industry for the synthesis of antibacterial and antineoplastic drugs.
Preparation Method:
-Generally, Pyridine-2-carboxylic acid (2-amino-ethyl)-amide can be synthesized by the following steps:
1. First, pyridine -2-carboxylic acid is reacted with 2-aminoethanol to generate pyridine -2-carboxylic acid (2-aminoethyl) ester.
2. Next, pyridine-2-carboxylic acid (2-aminoethyl) ester is reacted with hydrochloric acid to produce pyridine-2-carboxylic acid (2-aminoethyl) ester salt.
3. Finally, pyridine -2-carboxylic acid (2-aminoethyl) ester salt is reacted with ammonia to generate Pyridine-2-carboxylic acid (2-amino-ethyl)-amide.
Safety Information:
- Pyridine-2-carboxylic acid (2-amino-ethyl)-amide is less toxic and irritant.
-During use, avoid inhalation or contact with skin and eyes.
-Appropriate personal protective measures should be taken during handling and storage, such as wearing gloves, goggles and protective equipment.
-If inhaled or touched, wash the affected area promptly and seek medical advice.
Although this information is relatively safe for general use of the compound, caution is recommended in the use and handling of the compound, and reference is made to relevant safety materials and laboratory procedures.
Last Update:2024-04-09 21:01:54