104040-75-7

104040-75-7 - Names and Identifiers

Name	3-(trifluoromethyl) pyridine-2-sulfonyl chloride
Synonyms	3-(trifluoromethyl)-2-Pyridinesulfonyl chloride 3-(Trifluoromethyl)- pyridin-2-sulfonyl chloride 3-(trifluoromethyl) pyridine-2-sulfonyl chloride 3-(trifluoromethyl) pyridine-2-sulfonyl chloride
CAS	104040-75-7

104040-75-7 - Physico-chemical Properties

Molecular Formula	C6H3ClF3NO2S
Molar Mass	245.61
Storage Condition	Room Temprature

104040-75-7 - Introduction

3-Trifluoromethylpyridine-2-sulfonyl chloride is a common reagent in organic synthesis. The following is a description of its nature, use, preparation and safety information:

Nature:
The chemical formula of 3-trifluoromethylpyridine-2-sulfonyl chloride is C6H2ClF3NO2S, and the appearance thereof is a colorless liquid. It has a strong pungent odor and is easily soluble in most organic solvents.

Use:
3-Trifluoromethylpyridine-2-sulfonyl chloride is widely used in organic synthesis, and is often used as acylation and electrophilic sulfonylation reagent. It can convert the alcohol, acid or carbonate in the reactant to the corresponding acid chloride derivative. In addition, it can also be used to prepare organic compounds such as amides, imides and acid chlorides.

Preparation Method:
The preparation of 3-trifluoromethylpyridine-2-sulfonyl chloride generally adopts chemical synthesis method. Specific steps include reacting 3-trifluoromethylpyridine with sulfoxide, followed by sulfonylation with the addition of thionyl chloride.

Safety Information:
3-Trifluoromethylpyridine-2-sulfonyl chloride is an irritating chemical that may cause irritation in direct contact with the skin and eyes. When using should pay attention to wear protective gloves, glasses and protective clothing; avoid inhalation of its vapor, should be used in a well-ventilated place. In addition, should be stored in a dry, sealed container, away from fire and flammable materials. For accidental contact or ingestion, seek medical attention promptly.

Last Update：2024-04-10 22:29:15