10441-57-3

10441-57-3 - Names and Identifiers

Name	1-METHYLPYRROLIDINE-2-THIONE
Synonyms	1-Methyl-2-pyrrolidinethione 1-methyl-2-pyrrolidinethione 1-METHYLPYRROLIDINE-2-THIONE 1-Methylpyrrolidine-2-thione 2-Pyrrolidinethione, 1-methyl- 2-Pyrrolidinethione, 1-Methyl-
CAS	10441-57-3
InChI	InChI=1/C5H9NS/c1-6-4-2-3-5(6)7/h2-4H2,1H3

10441-57-3 - Physico-chemical Properties

Molecular Formula	C5H9NS
Molar Mass	115.2
Density	1.09
Melting Point	16 °C
Boling Point	145 °C / 15mmHg
Flash Point	45.5°C
Vapor Presure	3.63mmHg at 25°C
Appearance	clear liquid
Color	Light yellow to Brown
pKa	1.74±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5830 to 1.5870

10441-57-3 - Introduction

1-Methylpyrrolidine-2-thione (also known as methylpyrrolidinethione) is an organosulfur compound with the chemical formula C5H7NOS. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1-Methylpyrrolidine-2-thione is a white to off-white solid with a distinctive thiols odor. It has a melting point of about 35-39 degrees Celsius and a boiling point of about 165-169 degrees Celsius. This compound is practically insoluble in water, but soluble in common organic solvents.

Use:
1-Methylpyrrolidine-2-thione is commonly used as a chemical reagent and intermediate. It can be used in the synthesis of other organic sulfur compounds, such as carbazolthione, thiazinthione, etc. In addition, it can also be used in organic synthesis of sulfurization reaction, sulfurization reduction reaction and sulfurization reaction.

Preparation Method:
A common method for preparing 1-methylpyrrolidine-2-thione is through a nucleophilic substitution reaction of the pyrrolidine ring. A common synthetic method is to react 1-methylpyrrolidine with sodium oxysulfide to form 1-methylpyrrolidine-2-sulfoxide, which is then reduced to 1-methylpyrrolidine-2-thione.

Safety Information:
1-Methylpyrrolidine-2-thione is flammable under high temperature and open flame. It may cause an explosive mixture to the air. Care should be taken to avoid inhalation, contact with skin and ingestion. Wear appropriate protective equipment, such as gloves, safety glasses and face shields. When handling it, maintain good ventilation conditions. In case of exposure to the substance, the affected area should be promptly flushed with plenty of water, and in case of discomfort, seek medical advice and treatment.

Last Update：2024-04-10 22:29:15