104798-53-0

104798-53-0 - Names and Identifiers

Name	2-Fluoro-5-hydroxybenzenecarbonitrile
Synonyms	QR DF CCN 3-Cyano-4-fluorophenol 2-Fluoro-5-hydroxybenzene Fluoro-5-hydroxybenzonitrile 2-fluoro-5-hydroxybenzonitrile 2-Fluoro-5-hydroxybenzonitrile Benzonitrile, 2-fluoro-5-hydroxy- benzonitrile, 2-fluoro-5-hydroxy- 2-Fluoro-5-hydroxybenzenecarbonitrile
CAS	104798-53-0
InChI	InChI=1/C7H4FNO/c8-7-2-1-6(10)3-5(7)4-9/h1-3,10H

104798-53-0 - Physico-chemical Properties

Molecular Formula	C7H4FNO
Molar Mass	137.11
Density	1.34
Melting Point	111-113°
Boling Point	268℃
Flash Point	116℃
Vapor Presure	0.00473mmHg at 25°C
pKa	8.59±0.18(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	IRRITANT
Refractive Index	1.558
MDL	MFCD11846514

104798-53-0 - Risk and Safety

Hazard Class

IRRITANT

104798-53-0 - Introduction

2-Fluoro-5-hydroxybenzonitrile is an organic compound with the chemical formula C6H4FNO. The following is a description of its nature, use, formulation and safety information:

Nature:
2-Fluoro-5-hydroxybenzonitrile is a colorless crystal and is hygroscopic. It has a melting point of 125-128 degrees Celsius and a boiling point of 283-285 degrees Celsius. It is sparingly soluble in water and soluble in ethanol and ether.

Use:
2-Fluoro-5-hydroxybenzonitrile is an important intermediate in organic synthesis. It can be used in the synthesis of pesticides, pharmaceuticals and other organic compounds. Due to its receptor-binding properties, it can also be used as a building block for biologically active molecules.

Preparation Method:
The preparation of 2-fluoro-5-hydroxybenzonitrile can be completed by the reduction reaction of 2-fluoro-5-nitrobenzonitrile. Typically, this reaction can be accomplished using a metal reducing agent such as zinc and acetic acid, or a reducing agent such as a sulfoxide or sodium sulfoxide.

Safety Information:
When handling 2-fluoro-5-hydroxybenzonitrile, care should be taken to prevent contact with eyes, skin and respiratory tract. If contact with the skin, should immediately rinse with plenty of water. If inhaled or swallowed by mistake, should be sent to hospital for treatment immediately. In addition, use should wear appropriate protective measures, such as protective glasses and protective gloves. Avoid contact with oxidants and acids to avoid dangerous reactions.

Last Update：2024-04-09 21:04:16