1049734-91-9
Methyl 2-amino-6-isopropyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylate hydrate
CAS: 1049734-91-9
Molecular Formula: C12H20N2O3S
1049734-91-9 - Names and Identifiers
1049734-91-9 - Physico-chemical Properties
| Molecular Formula | C12H20N2O3S |
| Molar Mass | 272.36 |
| Melting Point | 92-94 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD06411621 |
1049734-91-9 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
1049734-91-9 - Introduction
Nature:
-Appearance: A white to light yellow crystalline powder.
-Formula: C13H19N3O3S · H2O
-Molecular weight: 313.38g/mol
-melting point: about 130-134 ℃
-Solubility: Soluble in organic solvents, such as chloroform, ethanol and dimethyl sulfoxide.
-Chemical properties: The compound is an ester compound, containing amino and thiophene rings. It has a certain chemical stability.
Use:
-Pharmaceutical field: Methyl 2-amino-6-isopropyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylate hydrate is an intermediate compound for the synthesis of fluorescein in granulomimetic bacteria. Granulosa fluorescein is widely used in biomedical research, such as bioimaging and cell tracing.
-Other aspects: Because the compound has a unique chemical structure, it can also be used as an intermediate in organic synthesis.
Preparation Method:
Methyl 2-amino-6-isopropyl-4,5,6,7-tetrahydro-thieno[2,3-c] The preparation of pyridine-3-carboxylate hydrate usually includes the following steps:
1. The thiophene ring was synthesized by an appropriate method. For example, by a condensation reaction of thiophene and propylene glycol or by a reaction of a carbonyl compound and sulfur.
2. Synthesis of 2-[(tert-butoxycarbonyl)amino]acetaldehyde, and then with the thiophene ring olefin group transfer reaction.
3. Finally, through a series of simplified reaction steps and purification process, the final product was obtained.
Safety Information:
There is a lack of public information about the specific safety of the compound, so detailed safety information cannot be given directly. However, based on the structure of this compound and the general properties of similar compounds, it is speculated that it may have certain irritating and common risks of organic synthetic chemicals. Therefore, when using the compound, it is necessary to strictly follow the relevant laboratory safety procedures, such as wearing appropriate personal protective equipment, avoiding contact with skin and eyes, avoiding inhalation and ingestion, etc. During handling and storage, please observe the general safety requirements for chemicals to ensure personal safety and laboratory safety.
Last Update：2024-04-09 21:54:55
