1052714-46-1

1052714-46-1 - Names and Identifiers

Name	6-Bromo-5-fluoropyridine-2-carboxylic acid
Synonyms	6-BroMo-5-fluoropicolinic acid 6-Bromo-5-fluoro-2-pyridinecarboxylic acid 6-Bromo-5-fluoropyridine-2-carboxylic acid 2-Pyridinecarboxylic acid, 6-broMo-5-fluoro-
CAS	1052714-46-1
InChI	InChI=1S/C6H3BrFNO2/c7-5-3(8)1-2-4(9-5)6(10)11/h1-2H,(H,10,11)

1052714-46-1 - Physico-chemical Properties

Molecular Formula	C6H3BrFNO2
Molar Mass	220
Density	1.903
Boling Point	331.3±42.0 °C(Predicted)
pKa	3.19±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

1052714-46-1 - Risk and Safety

UN IDs

UN2811

1052714-46-1 - Introduction

6-bromo-5-fluoro-2-picolinic acid, also known as 5-fluoro-2-bromopicolinic acid, chemical formula C6H3BrFNOC, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless crystal
-melting point: 155-157 ℃
-Boiling point: 355 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as ether, chloroform and methanol

Use:
6-Bromo-5-fluoro-2-picolinic acid is mainly used as a catalyst or ligand in organic synthesis. It can be used for the synthesis of compounds containing 5-fluoro-2-bromopyridine structure, such as heterocyclic compounds in organic synthesis, drugs, pesticides and other organic chemistry research.

Preparation Method:
There are many ways to prepare 6-bromo-5-fluoro-2-picolinic acid. The following is one of the commonly used methods:
In a reactor, 5-fluoro-2-pyridinecarboxylic acid is reacted with concentrated bromine solution, and the product of 6-bromo-5-fluoro-2-pyridinecarboxylic acid is obtained through the steps of reaction, separation and crystallization.

Safety Information:
1. 6-Bromo-5-fluoro-2-picolinic acid Avoid contact with skin and eyes during handling and storage to prevent inhalation or swallowing.
2. Wear appropriate protective equipment such as lab gloves, goggles and protective clothing when handling this compound.
3. Make sure to operate in a well-ventilated area and keep away from fire and heat sources.
4. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help if necessary.
5. When storing, it should be stored in a sealed container and placed in a dry and cool place, away from combustibles and oxidants.

Be sure to read and follow the relevant safety instructions and precautions before using 6-bromo-5-fluoro-2-picolinic acid.

Last Update：2024-04-09 15:17:50