1065183-64-3

1065183-64-3 - Names and Identifiers

Name	1H-Indole-1-carboxylic acid, 6-fluoro-2,3-dihydro-, 1,1-diMethylethyl ester
Synonyms	tert-Butyl 6-fluoroindoline-1-carboxylate tert-Butyl 6-fluoro-2,3-dihydro-1H-indole-1-carboxylate 1H-Indole-1-carboxylic acid, 6-fluoro-2,3-dihydro-, 1,1-diMethylethyl ester
CAS	1065183-64-3

1065183-64-3 - Physico-chemical Properties

Molecular Formula	C13H16FNO2
Molar Mass	237.27
Storage Condition	2-8°C

1065183-64-3 - Introduction

1-tert-butoxycarbonyl-6-fluoroindoline is an organic compound with the chemical formula C14H16FNO2.

Its properties include:
-Appearance: White crystalline solid
-Melting point: about 60-62 degrees Celsius
-Solubility: Soluble in common organic solvents such as ether, methanol and dichloromethane
-Molecular weight: about 263.28g/mol

The main uses of 1-tert-butoxycarbonyl-6-fluoroindoline are:
-Synthetic drugs: It is an important intermediate that can be used to synthesize drugs and biologically active substances. For example, it can be used to synthesize compounds with anti-cancer activity.
-Organic synthesis: It can be used as a reagent or catalyst in organic synthesis reactions, such as fluorination reactions and electrophilic substitution reactions.

A common method for preparing 1-tert-butoxycarbonyl-6-fluoroindoline is through a reaction sequence: first, indoline is reacted with hydrofluoric acid to obtain 6-fluoroindoline; then, it is reacted with tert-Butoxycarbonyl-6-fluoroindoline to generate 1-tert-butoxycarbonyl-6-fluoroindoline.

Regarding safety information, you need to pay attention:
-1-tert-butoxycarbonyl-6-fluoroindoline is an organic compound with potential toxicity and irritation. In the process of use, must strictly abide by the laboratory safety operation procedures.
-Avoid contact with skin, eyes and respiratory tract, and avoid inhaling dust or gas. Appropriate protective equipment such as gloves, goggles and protective masks should be worn during operation.
-During storage and handling, avoid contact with oxidants and strong acids to prevent dangerous reactions.
-In the event of accidental splash or inhalation, immediately stay away from the scene, breathe in a well-ventilated place, and seek medical attention if necessary.

Last Update：2024-04-09 21:01:54