Molecular Formula | C4H4NNaO6S |
Molar Mass | 217.13 |
Melting Point | 250°C (dec.)(lit.) |
Water Solubility | Soluble in methanol and water. |
Solubility | Soluble in Methanol and Water |
Appearance | White to yellowish powder |
Color | White |
BRN | 6359129 |
Storage Condition | Inert atmosphere,2-8°C |
Sensitive | Humidity sensitivity |
MDL | MFCD00043100 |
Physical and Chemical Properties | Storage Conditions: 0-6 ℃ WGK Germany:3 |
Use | Polypeptide condensing agent can form a stable active ester intermediate. Used to prepare hydrophilic active esters, such as as protein crosslinking agents. |
In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
TSCA | Yes |
HS Code | 29280000 |
Reference Show more | 1. Zhao Delu, Tie Chaorong, Yang Xisi, et al. Preparation and Characterization of Sodium Methacrylate Modified Photocrosslinked Alginate Hydrogel Scaffold [J]. China Tissue Engineering Research, 2020, 024(022):3445-3451. 2. [IF = 3.266] Zhengsong Yu et al."Highly efficient electrochemical detection of lead ion using metal-organic framework and graphene as platform based on DNAzyme." Synthetic Met. 2019 Aug;254:164 3. [IF = 4.375] Zha Quanbin et al."Preparation and Study of Folate Modified Albumin Targeting Microspheres." J Oncol. 2022;2022:3968403 |
biological activity | N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker that can be used to synthesize antibody-coupled drugs (ADC). |
uses | raw materials for scientific research polypeptide condensing agent can form stable active ester intermediates. Used to prepare hydrophilic active esters, such as as protein crosslinking agents. Used to activate carboxylic acids of interest to more reactive succinimide esters, for coupling, biotinylation and binding to fluorophores. Also used for crosslinking agents. |