107099-99-0

107099-99-0 - Names and Identifiers

Name	2,5-Dimethoxybenzeneboronic acid
Synonyms	AKOS BRN-0036 2,5-DIMETHOXYPHENYLBORONIC ACID 2,5-Dimethoxyphenylboronic acid 2,5-Dimethoxybenzeneboronic acid 2,5-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride)
CAS	107099-99-0
EINECS	679-699-5
InChI	InChI=1/C8H11BO4/c1-12-6-3-4-8(13-2)7(5-6)9(10)11/h3-5,10-11H,1-2H3
InChIKey	QOZLFNQLIKOGDR-UHFFFAOYSA-N

107099-99-0 - Physico-chemical Properties

Molecular Formula	C8H11BO4
Molar Mass	181.98
Density	1.19±0.1 g/cm3(Predicted)
Melting Point	95-98 °C (lit.)
Boling Point	374.5±52.0 °C(Predicted)
Flash Point	180.3°C
Vapor Presure	2.84E-06mmHg at 25°C
Appearance	White crystalline powder
BRN	2969872
pKa	8.12±0.58(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.517
MDL	MFCD01318181

107099-99-0 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29319090
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

107099-99-0 - Introduction

2,5-dimethoxybenzene boronic acid, chemical formula C9H11BO4, is an organic boron compound. The following is an introduction to its nature, use, formulation and safety information:

Nature:
-Appearance: 2,5-dimethoxybenzene boronic acid is a white crystalline solid.
-Melting point: Its melting point is about 106-108 degrees Celsius.
-Solubility: It is slightly soluble in water and insoluble in organic solvents such as alcohols and ethers.

Use:
-Catalyst: 2,5-dimethoxybenzene boronic acid is often used as the ligand of asymmetric catalyst, participates in organic synthesis reaction, and can effectively catalyze asymmetric addition reaction and asymmetric hydrogenation reaction.
-Organic synthesis: It can be used to prepare drugs and other organic molecules, such as sugars, hormones, natural products, etc.

Preparation Method:
2,5-Dimethoxybenzene boronic acid is usually synthesized by the following steps:
1. Methylation along two positions on the aromatic ring can obtain 2,5-dimethoxybenzaldehyde.
2. react 2,5-dimethoxybenzaldehyde with triphenylboron to generate 2,5-dimethoxybenzeneboronic acid.

Safety Information:
2,5-dimethoxybenzene boric acid is relatively safe under normal conditions of use, but the following matters still need to be paid attention:
-Avoid contact with skin and eyes, and rinse with plenty of water in time after contact.
-Wear appropriate eye protection and gloves during operation.
-Avoid inhaling its dust or gas, and operate in a well-ventilated place.
-Store away from ignition and oxidizing agents.

When using and handling 2,5-dimethoxyphenylboronic acid, it should be operated in accordance with the standard procedures for safe laboratory operations and chemical handling to ensure personal safety and the safety of the experimental environment.

Last Update：2024-04-09 19:05:44