1071455-14-5

1071455-14-5 - Names and Identifiers

Name	(3-Methyl-1H-pyrazol-4-yl)boronic acid
Synonyms	3-Methylpyrazole-4-boronic acid 3-Methyl-1H-pyrazole-4-boronic acid 3-Methyl-1H-pyrazol-4-ylboronic acid (3-Methyl-1H-pyrazol-4-yl)boronic acid Boronic acid, B-(3-methyl-1H-pyrazol-4-yl)-
CAS	1071455-14-5
InChI	InChI=1S/C4H7BN2O2/c1-3-4(5(8)9)2-6-7-3/h2,8-9H,1H3,(H,6,7)

1071455-14-5 - Physico-chemical Properties

Molecular Formula	C4H7BN2O2
Molar Mass	125.92
Density	1.31±0.1 g/cm3(Predicted)
Boling Point	415.8±47.0 °C(Predicted)
pKa	7.75±0.58(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

1071455-14-5 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

1071455-14-5 - Introduction

3-Methylpyrazole-4-boronic acid is an organic compound with the chemical formula C6H8BN3O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Methylpyrazole-4-boronic acid is a white to light yellow crystalline solid.
-Melting point: about 196-198 degrees Celsius.
-Solubility: Soluble in water and many organic solvents.

Use:
-Catalyst: 3-Methylpyrazole-4-boronic acid is commonly used as a catalyst for metal ions, especially for C- C bond formation in organic reactions.
-Buffer: It can be used as a buffer to adjust the pH of the solution.
-Coordination reagent: Because it contains a boronic acid group, it can be used to form complexes with metal ions.

Preparation Method:
3-Methylpyrazole-4-boronic acid can be prepared by the following steps:
1. the reaction of pyrazole with methyl trimethylsilylation reagent to generate 3-methyl pyrazole.
2. The generated 3-methyl pyrazole is reacted with boric acid to generate 3-methyl pyrazole -4-boronic acid.

Safety Information:
3-Methylpyrazole-4-boronic acid has low toxicity to human body. However, it is a chemical and the following safety measures should be taken when using it:
-Avoid contact with skin and eyes. Wear appropriate protective gloves and goggles when in use.
-Avoid inhaling the vapor of its dust or solution. Good ventilation should be ensured during operation, preferably in a chemical laboratory or ventilated environment.
-If you ingest or inhale the compound by accident, please consult a doctor immediately and bring the packaging or label for your doctor's reference.

Last Update：2024-04-10 22:29:15