1072946-54-3
(3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid
CAS: 1072946-54-3
Molecular Formula: C14H21BN2O3
1072946-54-3 - Names and Identifiers
1072946-54-3 - Physico-chemical Properties
| Molecular Formula | C14H21BN2O3 |
| Molar Mass | 276.14 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD11053842 |
1072946-54-3 - Introduction
(3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is an organic compound with the chemical formula C16H24BNO3.
Nature:
(3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is a white crystalline solid that can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO), N,N-dimethylformamide (DMF) and dichloromethane. It has the properties of a borate ester and can undergo a substitution reaction with another compound.
Use:
(3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is an important reagent in organic synthesis and is commonly used in Suzuki bonding reactions and Suzuki-Miyaura reactions. These reactions are commonly used methods to construct carbon-carbon bonds in organic synthesis, and can synthesize a variety of organic compounds, such as drugs, pesticides, dyes, etc.
Preparation Method:
the preparation method of (3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is relatively complicated. a common method is to react Piperidine with ethyl 2-bromoacetate to obtain 2-(Piperidin-1-yl)ethyl acetate, and then react with p-nitrobenzoic anhydride to obtain N-(2-(Piperidin-1-yl)ethyl)-4-nitrobenzamide. Finally, the final product (3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid was obtained by reaction with triethylamine and trifluoroboric acid.
Safety Information:
Less information has been reported on the toxicity of (3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid, but in general, chemicals should be stored and handled in a safe manner. Therefore, when using the compound, it is necessary to take appropriate protective measures, including wearing safety glasses, gloves and laboratory coats, and maintaining indoor ventilation. In addition, the compound should be stored away from ignition and oxidizing agents to prevent fire and explosion. Before use, it is recommended to understand and refer to the relevant safety data sheet (SDS) in detail.
Nature:
(3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is a white crystalline solid that can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO), N,N-dimethylformamide (DMF) and dichloromethane. It has the properties of a borate ester and can undergo a substitution reaction with another compound.
Use:
(3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is an important reagent in organic synthesis and is commonly used in Suzuki bonding reactions and Suzuki-Miyaura reactions. These reactions are commonly used methods to construct carbon-carbon bonds in organic synthesis, and can synthesize a variety of organic compounds, such as drugs, pesticides, dyes, etc.
Preparation Method:
the preparation method of (3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid is relatively complicated. a common method is to react Piperidine with ethyl 2-bromoacetate to obtain 2-(Piperidin-1-yl)ethyl acetate, and then react with p-nitrobenzoic anhydride to obtain N-(2-(Piperidin-1-yl)ethyl)-4-nitrobenzamide. Finally, the final product (3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid was obtained by reaction with triethylamine and trifluoroboric acid.
Safety Information:
Less information has been reported on the toxicity of (3-((2-(Piperidin-1-yl)ethyl)carbamoyl)-phenyl)boronic acid, but in general, chemicals should be stored and handled in a safe manner. Therefore, when using the compound, it is necessary to take appropriate protective measures, including wearing safety glasses, gloves and laboratory coats, and maintaining indoor ventilation. In addition, the compound should be stored away from ignition and oxidizing agents to prevent fire and explosion. Before use, it is recommended to understand and refer to the relevant safety data sheet (SDS) in detail.
Last Update：2024-04-09 21:54:55
