1072952-25-0 - Names and Identifiers
1072952-25-0 - Physico-chemical Properties
Molecular Formula | C7H8BFO3
|
Molar Mass | 169.95 |
Melting Point | 70-72°C |
Appearance | Crystallization |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
MDL | MFCD06656276 |
1072952-25-0 - Risk and Safety
Hazard Symbols | C - Corrosive
|
Hazard Class | IRRITANT |
1072952-25-0 - Introduction
2-Fluoro-5-hydroxymethylphenylboronic acid is an organic compound with the chemical formula C7H7BFO3. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Fluoro-5-hydroxymethylbenzeneboronic acid is a white or light yellow crystalline solid, soluble in water and organic solvents. Its pH value is low, weak acid.
Use:
2-Fluoro-5-hydroxymethylphenylboronic acid is often used as a reagent in organic synthesis. It can participate in various organic synthesis reactions such as boronic acid-catalyzed substitution reactions and metal-catalyzed coupling reactions. In addition, it can also be used as a precursor of functional materials for the preparation of fluorescent dyes, coatings, rubber additives, etc.
Preparation Method:
The preparation method of 2-fluoro-5-hydroxymethylphenylboronic acid is relatively simple. A common synthetic method is the heating reaction of 5-hydroxymethylsalicylic acid with boron trifluoride in the presence of hydrofluoric acid to produce the target product. Attention should be paid to operating conditions and safety protection during preparation.
Safety Information:
2-Fluoro-5-hydroxymethylphenylboronic acid is relatively stable under general operating conditions, but it is still necessary to comply with safe operating procedures. In case of contact with skin, eyes or inhalation, rinse immediately with plenty of water and seek medical assistance. During storage and handling, keep away from fire and oxidant to avoid violent friction and shock.
Last Update:2024-04-10 22:29:15