1077-97-0

1077-97-0 - Names and Identifiers

Name	5-iodo-1H-indazole-3-carboxylic acid
Synonyms	5-Iodoindazole-3-carboxylic acid 5-iodo-1H-indazole-3-carbaldehyde 5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID 5-iodo-1H-indazole-3-carboxylic acid 5-IODO-3-(1H)INDAZOLE CARBOXYLIC ACID 1H-Indazole-3-carboxylic acid, 5-iodo- 1H-indazole-3-carboxylic acid, 5-iodo-
CAS	1077-97-0 677702-22-6
InChI	InChI=1/C8H5IN2O/c9-5-1-2-7-6(3-5)8(4-12)11-10-7/h1-4H,(H,10,11)

1077-97-0 - Physico-chemical Properties

Molecular Formula	C8H5IN2O2
Molar Mass	288.04
Density	2.220±0.06 g/cm3(Predicted)
Melting Point	375℃
Boling Point	512.1±30.0 °C(Predicted)
Flash Point	217.2°C
Vapor Presure	8.66E-08mmHg at 25°C
pKa	2.84±0.30(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.824

1077-97-0 - Introduction

5-iodine -1H-indole oxazole -3-carboxylic acid is an organic compound, its chemical structure contains indole ring and formic acid group, at the same time there is an iodine atom substituted in the indole ring on the fifth carbon atom.

Regarding its properties, 5-iodo-1H-indolazole-3-carboxylic acid is a solid with the appearance of white crystals. Its melting point at room temperature and pressure is 192-196 degrees Celsius. This compound has a certain solubility and is soluble in common organic solvents such as methanol, ethanol and dimethylformamide.

5-iodo-1H-indolazole-3-carboxylic acid has certain application value in pharmaceutical chemistry, which is mainly used for the synthesis of biologically active compounds containing indole groups. Indole groups have a wide range of applications in medicinal chemistry, for example as precursors for anti-tumor, anti-inflammatory and anti-viral drugs.

The compound can be prepared by reacting indole with methyl iodide. First, indole is dissolved in an appropriate solvent, and methyl iodide is added as a substitution reagent, and the reaction is carried out under appropriate conditions. After completion of the reaction, the target product can be obtained through separation and purification.

Regarding safety information, 5-iodo-1H-indolazole-3-carboxylic acid requires personal protective measures when handling. Wear appropriate protective gloves, glasses and laboratory clothing during operation to avoid contact with skin or inhalation of gases. In addition, chemicals need to be stored in a dark, dry and well-ventilated place, away from fire and oxidizing agents. When using the compound, correct operating procedures should be followed and the laboratory's safe operating instructions should be strictly followed.

Last Update：2024-04-09 21:54:55