Name | Poziotinib |
Synonyms | Poziotinib UNII-OEI6OOU6IK Poziotinib (HM781-36B) 1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one |
CAS | 1092364-38-9 |
Molecular Formula | C23H21Cl2FN4O3 |
Molar Mass | 491.342 |
Density | 1.409±0.06 g/cm3(Predicted) |
Melting Point | 187 - 190° C |
Boling Point | 629.7±55.0 °C(Predicted) |
Appearance | Shape Solid, color White to Pale Beige |
pKa | 5.35±0.30(Predicted) |
Storage Condition | -20°C Freezer, Under inert atmosphere |
Raw Materials | Intermediate 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate Intermediate 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol 3,4-Dichloro-2-fluoroaniline Acryloyl chloride |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.035 ml | 10.176 ml | 20.352 ml |
5 mM | 0.407 ml | 2.035 ml | 4.07 ml |
10 mM | 0.204 ml | 1.018 ml | 2.035 ml |
5 mM | 0.041 ml | 0.204 ml | 0.407 ml |