109299-79-8
2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE
CAS: 109299-79-8
Molecular Formula: C12H21BN2O4
109299-79-8 - Names and Identifiers
| Name | 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE |
| Synonyms | [2,4-bis(tert-butoxy)pyriMidin-5-yl]boronic acid 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE |
| CAS | 109299-79-8 |
| EINECS | 220-753-0 |
109299-79-8 - Physico-chemical Properties
| Molecular Formula | C12H21BN2O4 |
| Molar Mass | 268.12 |
| Storage Condition | 2-8°C |
109299-79-8 - Upstream Downstream Industry
| Raw Materials | 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE |
109299-79-8 - Introduction
2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE is an organic compound with the chemical formula C13H23BN2O4. It is a white solid, soluble in some organic solvents, such as dimethylbenzene. It can be used as an intermediate and ligand in chemical synthesis.
2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE is often used as a deprotection reagent in organic synthesis to remove protecting groups in molecules. In addition, it can also be used as a ligand for metal catalysts and participate in a series of chemical reactions, such as coupling reactions, cross-coupling reactions, etc.
The method for preparing 2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE is generally carried out by reacting 2,4-di-tert-butoxypyrimidine and triphenylboron in the presence of sodium hydroxide and ammonium chloride. The specific preparation method is as follows:
Step 1: Mix 2,4-di-tert-butoxypyrimidine and triphenylboron in a molar ratio of 1:1;
Step 2: adding the mixture into an aqueous sodium hydroxide solution, stirring and reacting for several hours;
Step 3: Add ammonium chloride to precipitate to generate 2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE.
Step 4: The pure product was obtained by filtration and washing.
Regarding safety information, the specific toxicity and danger of 2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE has not been fully established. In general, however, it should be considered as a potential organic aerosol and should be used with appropriate protective equipment to avoid inhalation, contact with skin and eyes. During use and storage, attention should be paid to the accumulation of fire sources and static electricity, and good ventilation should be maintained. To ensure safety, this compound is best handled by experienced operators in a chemical laboratory.
2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE is often used as a deprotection reagent in organic synthesis to remove protecting groups in molecules. In addition, it can also be used as a ligand for metal catalysts and participate in a series of chemical reactions, such as coupling reactions, cross-coupling reactions, etc.
The method for preparing 2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE is generally carried out by reacting 2,4-di-tert-butoxypyrimidine and triphenylboron in the presence of sodium hydroxide and ammonium chloride. The specific preparation method is as follows:
Step 1: Mix 2,4-di-tert-butoxypyrimidine and triphenylboron in a molar ratio of 1:1;
Step 2: adding the mixture into an aqueous sodium hydroxide solution, stirring and reacting for several hours;
Step 3: Add ammonium chloride to precipitate to generate 2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE.
Step 4: The pure product was obtained by filtration and washing.
Regarding safety information, the specific toxicity and danger of 2,4-di (TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE has not been fully established. In general, however, it should be considered as a potential organic aerosol and should be used with appropriate protective equipment to avoid inhalation, contact with skin and eyes. During use and storage, attention should be paid to the accumulation of fire sources and static electricity, and good ventilation should be maintained. To ensure safety, this compound is best handled by experienced operators in a chemical laboratory.
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: 2,4-Ditert-butoxypyrimidin-5-ylboronic acid Visit Supplier Webpage Request for quotation
CAS: 109299-79-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 109299-79-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 2,4-Ditert-butoxypyrimidin-5-ylboronic acid Visit Supplier Webpage Request for quotation
CAS: 109299-79-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 109299-79-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for 109299-79-8