1093865-65-6

1093865-65-6 - Names and Identifiers

Name	4-Fluoro-3-formylbenzoic acid methyl ester
Synonyms	Methyl 4-fluoro-3-formylbenzoate Methyl 4-fluoro-3-forMylbenzoate 4-Fluoro-3-formylbenzoic acid methyl ester Benzoic acid, 4-fluoro-3-formyl-, methyl ester
CAS	1093865-65-6
InChI	InChI=1S/C9H7FO3/c1-13-9(12)6-2-3-8(10)7(4-6)5-11/h2-5H,1H3

1093865-65-6 - Physico-chemical Properties

Molecular Formula	C9H7FO3
Molar Mass	182.15
Density	1.271
Boling Point	275℃
Flash Point	117℃
Storage Condition	Inert atmosphere,Room Temperature

1093865-65-6 - Introduction

Methyl 4-fluoro-3-carbaldehyde benzoate, chemical formula C8H7FO3, is also known as FMOC methyl ester. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid.
-Melting point: about 54-56 degrees Celsius.
-Stability: Stable at room temperature, but can be decomposed at high temperature.
-Solubility: Soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, slightly soluble in ethanol and benzene.

Use:
-as a protecting group in organic synthesis: 4-fluoro-3-carbaldehyde benzoic acid methyl ester can be used as a cis-protecting group in the synthesis. It can protect the amino, hydroxyl and other functional groups to prevent them from unnecessary reactions.
-Chemical synthesis: It can be used to synthesize chemicals containing aromatic compounds, such as pharmaceutical intermediates, heterocyclic compounds, etc.

Preparation Method:
The preparation of 4-fluoro-3-formaldehyde benzoic acid methyl ester is mainly based on organic synthesis methods. One commonly used method of preparation is the reaction of methyl ketone with p-fluorobenzoic anhydride to obtain methyl 4-fluoro-3-carbaldehyde benzoate.

Safety Information:
-Irritating and corrosive to the skin, avoid contact with the skin.
-May cause serious irritation and damage to eyes, should avoid contact with eyes.
-Women who may be infected with the fetus should take precautions to avoid exposure to this compound.
-Pay attention to good ventilation during use to prevent its vapor from accumulating in the air and causing poisoning.
-Waste should be disposed of in a safe manner, following local rules and regulations.

Last Update：2024-04-09 02:00:41