11033-64-0 - Names and Identifiers
Name | N-deacetyllappaconitine
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Synonyms | Puberanidine N-deacetyllappaconitine Lappaconitine, deacetyl- 4-Anthraniloyllappaconine DEACETYLLAPPACONITINE (N-) Lappaconine, 4-(2-aminobenzoate) 20-Ethyl-1α,14α,16β-trimethoxyaconitane-4,8,9-triol 4-(2-aminobenzoate) Aconitane-4,8,9-triol, 20-ethyl-1,14,16-trimethoxy-, 4-(2-aminobenzoate), (1α,14α,16β)-
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CAS | 11033-64-0
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11033-64-0 - Physico-chemical Properties
Molecular Formula | C30H42N2O7
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Molar Mass | 542.66 |
Density | 1.35±0.1 g/cm3(Predicted) |
Melting Point | 218-220 °C(Solv: methanol (67-56-1)) |
Boling Point | 650.9±55.0 °C(Predicted) |
pKa | 12.56±0.70(Predicted) |
Storage Condition | 2-8℃ |
11033-64-0 - Reference
Reference Show more | 1. [IF=3.845] Zhang Yu et al."Integrating Pharmacokinetics Study, Network Analysis, and Experimental Validation to Uncover the Mechanism of Qiliqiangxin Capsule Against Chronic Heart Failure."Front Pharmacol. 2019 Sep;0:1046 |
11033-64-0 - Introduction
N-deacetyllappaconitine is a natural compound, which belongs to one of the active ingredients of Aconitum aconitum. The following is a description of its nature, use, preparation and safety information:
Nature:
N-deacetyllappaconitine is a white crystalline powder with a bitter and spicy taste. It is almost insoluble in water, but can be dissolved in organic solvents. Chemically, it is a derivative of N-desacetylaconitine.
Use:
N-deacetyllappaconitine is used in Chinese medicine to treat rheumatism, pain and rheumatoid arthritis. It is considered to have analgesic, anti-inflammatory and sedative pharmacological effects.
Method:
N-deacetyllappaconitine is mainly obtained by extracting from the root, rhizome or root block of Aconitum Thorn. The extraction process usually uses solvents such as water, ether or acetone. After extraction, the N-deacetyllappaconitine was isolated and purified by crystallization.
Safety Information:
N-deacetyllappaconitine is a toxic compound and should be used and stored with care. It may have irritating and toxic effects on the human body, and may be harmful to the central nervous system in high doses or long-term use. Therefore, its use in the field of medicine needs professional guidance and supervision. During use, attention should be paid to the use of safety measures and follow relevant safety operation procedures.
Last Update:2024-04-09 02:00:52