Name | OLIGOMYCIN C |
Synonyms | Oligmycin C OLIGOMYCIN C 12-Deoxyoligomycin A Oligomycin A, 12-deoxy- OLIGOMYCIN C, STREPTOMYCES DIASTATOCHROMOGENES Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11S,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)- |
CAS | 11052-72-5 |
EINECS | 234-276-0 |
Molecular Formula | C45H74O10 |
Molar Mass | 775.06 |
Density | 1.091 g/cm3 |
Boling Point | 876.2±65.0 °C(Predicted) |
Appearance | White to off-white powder. |
Merck | 13,6902 |
pKa | 13.49±0.70(Predicted) |
Storage Condition | −20°C |
In vitro study | Interaction of oligomycin C with purified CYP107W1 results in a type I binding with K d value of 14.4 μM. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
UN IDs | 2811 |
RTECS | RK3335000 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | LD50 ipr-mus: 8300 mg/kg JACSAT 80,6092,1958 |
biological activity | Oligomycin C is a macrolide antibiotic produced by Streptomyces. Oligomycin C showed strong anti-Aspergillus niger activity against Aspergillus niger,Alternaria alternata,Botrytis cinerea,Phytophthora capsici, but no activity against bacteria. |
in vitro study | Interaction of oligomycin C with purified CYP107W1 results in a type I binding with K d value of 14.4 μ m. |