111047-53-1
METHYL N-P-TOLUENESULFONYL-D-2-PHENYLGLYCINATE
CAS: 111047-53-1
Molecular Formula: C16H17NO4S
111047-53-1 - Names and Identifiers
| Name | METHYL N-P-TOLUENESULFONYL-D-2-PHENYLGLYCINATE |
| Synonyms | METHYL N-P-TOLUENESULFONYL-D-2-PHENYLGLYCINATE D-Methyl2-(4-MethylphenylsulfonaMido)-2-phenylacetate (R)-Methyl 2-(4-MethylphenylsulfonaMido)-2-phenylacetate (R)-Phenyl-(toluene-4-sulfonylamino)-acetic acid methyl ester methyl (2R)-{[(4-methylphenyl)sulfonyl]amino}(phenyl)ethanoate 2-[(4-methylphenyl)sulfonylamino]-2-phenylacetic acid methyl ester Benzeneacetic acid, α-[[(4-methylphenyl)sulfonyl]amino]-, methyl ester, (αR)- |
| CAS | 111047-53-1 |
| InChI | InChI=1/C16H17NO4S/c1-12-8-10-14(11-9-12)22(19,20)17-15(16(18)21-2)13-6-4-3-5-7-13/h3-11,15,17H,1-2H3/t15-/m1/s1 |
111047-53-1 - Physico-chemical Properties
| Molecular Formula | C16H17NO4S |
| Molar Mass | 319.38 |
| Density | 1.256±0.06 g/cm3(Predicted) |
| Melting Point | 128.0-129.0 °C |
| Boling Point | 473.5±55.0 °C(Predicted) |
| Flash Point | 240.1°C |
| Vapor Presure | 3.92E-09mmHg at 25°C |
| pKa | 8.96±0.50(Predicted) |
| Refractive Index | 1.577 |
111047-53-1 - Introduction
R-Phenyl-(p-toluenesulfonamido)-acetic acid methyl ester is an organic compound whose chemical formula is C16H17NO4S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
R-phenyl-(p-toluenesulfonamido)-methyl acetate is a colorless to light yellow liquid with a special smell. It is insoluble in water at room temperature, but soluble in most organic solvents. Its melting point and boiling point are -1°C and 272°C, respectively.
Use:
R-phenyl-(p-toluenesulfonamido)-acetic acid methyl ester is usually used as an intermediate in organic synthesis reactions. It can be used in the synthesis of drugs, pesticides and other organic compounds. In addition, it can also be used to prepare chemical products such as dyes, fragrances and high-end cosmetics.
Preparation Method:
The preparation method of R-phenyl-(p-toluenesulfonamido)-acetic acid methyl ester can be obtained by reacting methyl acetate with p-chlorotoluene sulfonyl chloride. The specific step is to react methyl acetate with p-chlorotoluene sulfonyl chloride in an inert solvent, then neutralize the reaction solution with dilute alkali, and then perform distillation purification to obtain the target product.
Safety Information:
R-Phenyl-(p-toluenesulfonamido)-acetic acid methyl ester is generally a low-risk substance under normal conditions of use and storage. However, it may be irritating to the eyes, skin and respiratory tract, so proper protective measures should be taken during operation, such as wearing chemical protective glasses, gloves and respiratory protective equipment. In addition, the substance should be kept away from ignition and heat sources, and stored in a cool, ventilated place to avoid direct contact with the skin and inhalation of its vapors. In case of leakage or accidental service, necessary emergency rescue measures should be taken in time and professionals should be consulted for help.
Nature:
R-phenyl-(p-toluenesulfonamido)-methyl acetate is a colorless to light yellow liquid with a special smell. It is insoluble in water at room temperature, but soluble in most organic solvents. Its melting point and boiling point are -1°C and 272°C, respectively.
Use:
R-phenyl-(p-toluenesulfonamido)-acetic acid methyl ester is usually used as an intermediate in organic synthesis reactions. It can be used in the synthesis of drugs, pesticides and other organic compounds. In addition, it can also be used to prepare chemical products such as dyes, fragrances and high-end cosmetics.
Preparation Method:
The preparation method of R-phenyl-(p-toluenesulfonamido)-acetic acid methyl ester can be obtained by reacting methyl acetate with p-chlorotoluene sulfonyl chloride. The specific step is to react methyl acetate with p-chlorotoluene sulfonyl chloride in an inert solvent, then neutralize the reaction solution with dilute alkali, and then perform distillation purification to obtain the target product.
Safety Information:
R-Phenyl-(p-toluenesulfonamido)-acetic acid methyl ester is generally a low-risk substance under normal conditions of use and storage. However, it may be irritating to the eyes, skin and respiratory tract, so proper protective measures should be taken during operation, such as wearing chemical protective glasses, gloves and respiratory protective equipment. In addition, the substance should be kept away from ignition and heat sources, and stored in a cool, ventilated place to avoid direct contact with the skin and inhalation of its vapors. In case of leakage or accidental service, necessary emergency rescue measures should be taken in time and professionals should be consulted for help.
Last Update：2024-04-09 20:52:54
