111258-23-2

111258-23-2 - Names and Identifiers

Name	methyl 4-methoxy-2-indolecarboxylate
Synonyms	AKOS JY2083512 METHYL 4-METHOXYINDOLE-2-CARBOXYLATE METHYL 4-METHOXY-2-INDOLECARBOXYLATE methyl 4-methoxy-2-indolecarboxylate methyl 4-methoxy-1H-indole-2-carboxylate METHYL 4-METHOXY-1H-INDOLE-2-CARBOXYLATE 4-METHOXY-2-INDOLECARBOXYLIC ACID METHYL ESTER 4-METHOXYINDOLE-2-CARBOXYLIC ACID METHYL ESTER 4-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID METHYL ESTER 4-methoxy-1H-Indole-2-carboxylic acid,methyl ester
CAS	111258-23-2
InChI	InChI=1/C11H11NO3/c1-14-10-5-3-4-8-7(10)6-9(12-8)11(13)15-2/h3-6,12H,1-2H3

111258-23-2 - Physico-chemical Properties

Molecular Formula	C11H11NO3
Molar Mass	205.21
Density	1.253±0.06 g/cm3(Predicted)
Melting Point	140-142°C(lit.)
Boling Point	370.1±22.0 °C(Predicted)
Flash Point	177.6°C
Vapor Presure	1.14E-05mmHg at 25°C
Appearance	White to slightly yellow crystalline powder
pKa	15.20±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.612
MDL	MFCD00134300

111258-23-2 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/38 - Irritating to eyes and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
HS Code	29339980

111258-23-2 - Introduction

4-methoxyindole-2-carboxylic acid methyl ester (methyl ester) is an organic compound with a chemical formula of C11H11NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-methoxyindole-2-carboxylic acid methyl ester is a white crystalline solid, which can vary from colorless to light yellow.
-Melting point: about 105 ℃-107 ℃.
-Storage conditions: need to be stored in a dry, dark, low temperature environment.

Use:
4-methoxyindole-2-carboxylic acid methyl ester is usually used as an intermediate in organic synthesis, mainly for the synthesis of natural products with indole skeleton, drugs and pesticides and other compounds. It can also be used to study indole derivatives for the preparation of new drug molecules.

Preparation Method:
The synthesis of 4-methoxyindole-2-carboxylic acid methyl ester can be achieved by the methylation of indole and the esterification of carboxylic acid. Specifically, methanol and an activated carboxylic acid can be used to react with the indole, followed by an esterification reaction to produce the target product.

Safety Information:
The toxicity information of 4-methoxyindole-2-carboxylic acid methyl ester is limited, so further evaluation and laboratory operation are required.
-Use with appropriate personal protective equipment, such as gloves and breathing apparatus.
-During operation, pay attention to prevent inhalation, contact with skin and eyes.
-During storage, avoid contact with fire and avoid contact with strong oxidants, strong acids and other substances.

Please note that the handling and use of chemicals should follow relevant safety procedures and comply with local laws and regulations.

Last Update：2024-04-09 20:49:11