112028-91-8

112028-91-8 - Names and Identifiers

Name	Diphenylmethyl 7beta-Tert-Butoxycarbonylamino-3-Chloromethyl-3-Cephem-4-Carboxylate
Synonyms	BOC-ACLH Diphenylmethyl 7beta-Tert-Butoxycarbonylamino-3-Chloromethyl-3-Cephem-4-Carboxylate (6R,7R)-Benzhydryl 7-((tert-butoxycarbonyl)amino)-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4 (6R,7R)-Benzhydryl 7-((tert-butoxycarbonyl)amino)-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2. (6R,7R)-Benzhydryl 7-((tert-butoxycarbonyl)aMino)-3-(chloroMethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate benzhydryl (6R,7R)-3-(chloromethyl)-7-[(2-methylpropan-2-yl)oxycarbonylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (6R,7R)-3-(Chloromethyl)-7-[[(tert-butoxy)carbonyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester (6R,7R)-3-(chloromethyl)-7-[[(1,1-dimethylethoxy)carbonyl]amino]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester
CAS	112028-91-8
EINECS	1312995-182-4

112028-91-8 - Physico-chemical Properties

Molecular Formula	C26H27ClN2O5S
Molar Mass	515.02
Density	1.36
Boling Point	685.7±55.0 °C(Predicted)
pKa	10.16±0.60(Predicted)
Storage Condition	2-8°C
Use	Cefoselis sulfate Intermediate

112028-91-8 - Introduction

7B-tert-Butoxycarbonylamino-3-chloromethyl-3-cephene-4-carboxylic acid diphenyl methyl ester, is an organic compound with the chemical formula C24H19ClNO7.

The compound has some of the following properties:
-Appearance: A white to yellow crystalline powder
-melting point: about 125 ℃-130 ℃
-Solubility: Good solubility in organic solvents, but relatively poor solubility in water

7B-tert-Butoxycarbonylamino-3-chloromethyl-3-cephem -4-carboxylic acid diphenyl methyl ester is an antibiotic. It is widely used to treat bacterial infections, particularly infectious diseases associated with cephalosporin-sensitive strains. It is commonly used in clinical treatment, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, such as a variety of infection symptoms.

The compounds are mainly prepared by chemical synthesis. The specific preparation method includes esterification reaction of cephalosporin C and tert-butyl benzoate, then introducing thionyl chloride and imine chloride into the reaction system, and finally obtaining the target product by acidolysis reaction.

Regarding the safety information of this compound, the following points need to be emphasized:
-The substance may be toxic to the human body, so you should pay attention to safe operation and follow relevant safety measures during use.
-Avoid contact with skin to avoid allergic reactions and irritation.
-During operation, you should avoid inhaling the dust or gas of this substance, because it may cause irritation and harm to the respiratory system.
-When dealing with 7B-tert-butoxycarbonylamino-3-chloromethyl-3-cephem-4-carboxylic acid diphenyl methyl ester, attention must be paid to proper discharge and disposal of waste to avoid environmental pollution.

Last Update：2024-04-10 22:29:15