112811-59-3
Gatifloxacin
CAS: 112811-59-3
Molecular Formula: C19H22FN3O4
112811-59-3 - Names and Identifiers
| Name | Gatifloxacin |
| Synonyms | AM1155 AM 1155 AM-1155 PD135432 Gatiquin PD-135432 PD 135432 GATIFLOXACIN Gatifloxacin BMS206584-01 BMS 206584-01 Gatifloxacin API 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-(3-METHYLPIPERAZIN-1-YL)-4-OXO-3-QUINOLINECARBOXYLIC ACID 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDROXY-8-METHOXY-7-(3-METHYL-1-PIPERAZINYL)-4-OXO-3-QUINOLINECARBOXYLIC ACID |
| CAS | 112811-59-3 |
| EINECS | 664-293-2 |
| InChI | InChI=1/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) |
112811-59-3 - Physico-chemical Properties
| Molecular Formula | C19H22FN3O4 |
| Molar Mass | 375.39 |
| Density | 1.386±0.06 g/cm3(Predicted) |
| Melting Point | 162°C |
| Boling Point | 607.8±55.0 °C(Predicted) |
| Flash Point | 321.4°C |
| Solubility | Soluble in water |
| Vapor Presure | 1.26E-15mmHg at 25°C |
| Appearance | White-like or light yellow crystalline powder |
| Color | White to Off-White |
| pKa | 6.43±0.50(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.616 |
| MDL | MFCD00895399 |
112811-59-3 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| HS Code | 29335990 |
112811-59-3 - Reference
| Reference Show more | 1. Shi Qingxin, Yang Yang, Cai Yingying, Zhou Tieli. Study on the resistance characteristics and molecular mechanism of multi-drug resistant Mycobacterium tuberculosis to quinolones [J]. Zhejiang Medicine, 2019,41(06):521-524 528. 2. Jiang Lijie, Liu Jian, Dong Yan. Distribution and drug resistance of pathogens causing nosocomial infection in children [J]. Chinese journal of pathogenic biology, 2019,14(07):840-843 847. 3. pan, ziyu, et al. "high-performance liquid chromatography study of gatifloxacin and sparfloxacin using erythrosine as post‐column resonance Rayleigh scattering reagent and mechanism study." Luminescence 33.2 (2018): 417-424.https://doi.org/10.1002/bio.3429 4. Xu, Meng, et al. "Chemical composition, antibacterial properties, and mechanism of Smilax china l. polyphenols." Applied microbiology and biotechnology 103.21 (2019): 9013-9022.https:// doi.org/10.1007/s00253-019-10100-0 5. [IF = 4.821] Ziyu Pan et al. "Simultaneous determination of five fluoroquinolones by the selective high performance liquid chromatography associating with sensitive resonance light scattering and mechanism study." Microchem J. 2018 Jan;136:71 6. [IF = 2.464] Ziyu Pan et al. "High-performance liquid chromatography study of gatifloxacin and sparfloxacin using erythrosine as post-column resonance Rayleigh scattering reagent and mechanism study." Luminescence. 2018 Mar;33(2): 417-424 7. [IF = 7.514] Bolong Fang et al. "Glucose oxidase-induced colorimetric immunoassay for qualitative detection of danofloxacin based on iron (Ⅱ) chelation reaction with phenanthroline." Food Chem. 2020 Oct;328:127099 8. [IF = 6.057] Song Hu et al. "Reliable performance of aggregation-induced emission nanoparticle-based lateral flow say for norfloxacin detection in nine types of animation-derived food." Talanta. 2020 Nov;219:121245 9. [IF = 4.813] Xu Meng et al. "Chemical composition, antibacterial properties, and mechanism of Smilax china L. polyphenols." Appl Microbiol Biot. 2019 Nov;103(21): 9013-9022 10. [IF = 5.293] Qian Weidong et al. "Antifungal and Antibiofilm Efficacy of Paeonol Treatment Against Biofilms Comprising Candida albicans and/or Cryptococcus neoformans." Frontiers in Cellular and Infection Microbiology. 2022 May;0:588 |
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