1128133-41-4
tert-Butyl 7-bromospiro[indoline-3,4'-piperidine]-1'-carboxylate
CAS: 1128133-41-4
Molecular Formula: C17H23BrN2O2
1128133-41-4 - Names and Identifiers
| Name | tert-Butyl 7-bromospiro[indoline-3,4'-piperidine]-1'-carboxylate |
| Synonyms | tert-Butyl 7-bromospiro[indoline-3,4'-piperidine]-1'-carboxylate tert-Butyl 7-broMospiro[indoline-3,4'-piperidine]-1'-carboxylate tert-butyl 7-bromo-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-carboxylate Spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 7-bromo-1,2-dihydro-, 1,1-dimethylethyl ester |
| CAS | 1128133-41-4 |
1128133-41-4 - Physico-chemical Properties
| Molecular Formula | C17H23BrN2O2 |
| Molar Mass | 367.28 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Boling Point | 461.7±45.0 °C(Predicted) |
| pKa | 3.50±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD12198578 |
1128133-41-4 - Introduction
tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is an organic compound whose chemical formula is C19H26BrN2O2. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is a solid substance.
-Solubility: It is soluble in common organic solvents.
Use:
- tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is a potential drug intermediate. It can be used to synthesize various drug molecules.
Preparation Method:
-Introduction of tert-butyl ester group: First, tert-butanol is reacted with 7-bromoindoline through a chemical reaction to form the tert-butyl alcohol ester derivative of 7-bromoindoline.
-Introduction of spiro structure: Subsequently, by reacting the tert-butyl alcohol ester derivative with piperidine, the target compound can be formed.
Safety Information:
- tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is an organic compound with certain toxicity. During operation, appropriate safety measures should be taken, such as wearing protective gloves and protective glasses.
-Due to insufficient human toxicity data, the potential hazard of this compound has not been fully established. Therefore, it is necessary to pay attention to the relevant safety operation specifications during use.
Nature:
-Appearance: tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is a solid substance.
-Solubility: It is soluble in common organic solvents.
Use:
- tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is a potential drug intermediate. It can be used to synthesize various drug molecules.
Preparation Method:
-Introduction of tert-butyl ester group: First, tert-butanol is reacted with 7-bromoindoline through a chemical reaction to form the tert-butyl alcohol ester derivative of 7-bromoindoline.
-Introduction of spiro structure: Subsequently, by reacting the tert-butyl alcohol ester derivative with piperidine, the target compound can be formed.
Safety Information:
- tert-Butyl 7-bromosspiro [indoline-3,4 '-piperidine]-1'-carboxylate is an organic compound with certain toxicity. During operation, appropriate safety measures should be taken, such as wearing protective gloves and protective glasses.
-Due to insufficient human toxicity data, the potential hazard of this compound has not been fully established. Therefore, it is necessary to pay attention to the relevant safety operation specifications during use.
Last Update：2024-04-09 21:04:16
