1129634-44-1 - Names and Identifiers
1129634-44-1 - Physico-chemical Properties
Molecular Formula | C12H19NO4
|
Molar Mass | 241.28 |
Density | 1.23±0.1 g/cm3(Predicted) |
Boling Point | 377.4±35.0 °C(Predicted) |
pKa | 4.04±0.20(Predicted) |
Storage Condition | 2-8°C |
Use | This product is for scientific research only and shall not be used for other purposes. |
1129634-44-1 - Introduction
(S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid, also known as S-Boc-5-azaspiro[2.4]heptane-6-carboxylic acid. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Usually white solid
-molecular formula: C, H, NO, NO.
-Molecular weight: 255.31g/mol
-Melting point: 110-112 degrees Celsius
Use:
- (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid is an organic compound, often used as a chiral reagent in organic synthesis, in particular, it is used as a chiral protecting group in acylation reactions. It can be used as an intermediate in the preparation of pharmaceuticals, pesticides, dyes and other organic compounds.
Preparation Method:
- (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4] The preparation of heptane-6-carboxylic acid can be carried out by the following steps:
1. React 5-azaspiro [2.4] heptane -6-carboxylic acid with the corresponding anhydride to generate the corresponding acid chloride.
2. Acid chloride reacts with tert-butoxyamine to form amide.
3. Finally, the amide is treated with acid to remove the protecting group to obtain the target product.
Safety Information:
- (S)-5-(tert-Butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic the safety of acid has not been fully established, it is important to follow laboratory safety procedures when using or handling it.
-It may be irritating to the eyes, skin and respiratory tract, so personal protective equipment such as lab gloves, goggles and protective masks should be used during operation.
-When stored, it should be kept in a sealed container, away from fire and oxidizing agents, and properly marked to avoid misuse or confusion.
Last Update:2024-04-09 21:00:56