113104-25-9
NSC228155
CAS: 113104-25-9
Molecular Formula: C11H6N4O4S
113104-25-9 - Names and Identifiers
| Name | NSC228155 |
| Synonyms | NSC228155 NSC 228155 NSC-228155 2-[(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio]pyridine 1-oxide |
| CAS | 113104-25-9 |
113104-25-9 - Physico-chemical Properties
| Molecular Formula | C11H6N4O4S |
| Molar Mass | 290.25 |
| Storage Condition | 2-8°C(protect from light) |
| In vitro study | NSC 228155 (100 μM) enhances EGFR tyrosine phosphorylation via action of SOD1. NSC 228155 (Compound 1) inhibits CREB- and VP16-CREB-mediated gene transcription in living HEK 293T cells with IC 50 s of 2.09 and 6.14 μM, respectively. NSC 228155 is not selective against CREB-mediated gene transcription in living HEK 293T cells. |
113104-25-9 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.445 ml | 17.227 ml | 34.453 ml |
| 5 mM | 0.689 ml | 3.445 ml | 6.891 ml |
| 10 mM | 0.345 ml | 1.723 ml | 3.445 ml |
| 5 mM | 0.069 ml | 0.345 ml | 0.689 ml |
Last Update：2024-01-02 23:10:35
113104-25-9 - Reference Information
| biological activity | NSC 228155 is an EGFR activator that binds to the extracellular domain of EGFR and induces phosphorylation of EGFR. NSC 228155 is a potent KIX-KID interaction inhibitor capable of inhibiting the interaction of the kinase-inducing domain (kid) of CREB and KIX (kidinteraction domain, derived from CBP), the IC50 value was 0.36 μm. |
Last Update：2024-04-09 21:04:16
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Product Name: NSC228155 Visit Supplier Webpage Request for quotationCAS: 113104-25-9
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Mobile: 18021002903
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Wechat: 18301782025
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