114224-27-0
1H-Indol-3-ol, 6-bromo-
CAS: 114224-27-0
Molecular Formula: C8H6BrNO
114224-27-0 - Names and Identifiers
| Name | 1H-Indol-3-ol, 6-bromo- |
| Synonyms | 6-BROMO-1H-INDOL-3-OL 1H-Indol-3-ol, 6-bromo- 1H-Indol-3-ol, 6-broMo- 1-Boc-6-broMo-1H-indol-3-ol 1-Boc-6-bromo-1H-indol-3-ol |
| CAS | 114224-27-0 |
114224-27-0 - Physico-chemical Properties
| Molecular Formula | C8H6BrNO |
| Molar Mass | 212.04 |
| Storage Condition | 2-8°C |
114224-27-0 - Introduction
1-tert-Butoxycarbonyl-6-bromo-3-ol-1H-indole, also known as 6-bromo-1H-indol-3-yl tert-butyl carbonate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Properties: 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole is a white solid. It has a molecular formula of C14H16BrNO3 and a molecular weight of 323.19g/mol. This compound is soluble in the solvent, but insoluble in water. Its melting point is 145-150 degrees Celsius. It is an organic compound containing in its structure the ring of indole and a carboxylic ester as well as a tert-butoxy group and a bromine atom.
Purpose: 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole has certain application potential in the pharmaceutical field and can be used as a pharmaceutical intermediate for the synthesis of biologically active compounds. Indole compounds have been widely used in drug research, with anti-inflammatory, anti-tumor and antibacterial activities.
Preparation method: 1-tert-butoxycarbonyl -6-bromo -3-ol -1H-indole can be obtained through a series of chemical reactions. First, indole is subjected to a substitution reaction with hydrobromic acid to give 6-bromoindole. The 6-bromoindole is then subjected to a condensation reaction with tert-butoxyhydroxyformate, catalyzed by a base, to yield 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole.
Safety information: Since 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole is an organic compound, like all chemicals, it must be handled in a laboratory environment. The safe handling of chemicals must be strictly followed at the time of contact, including the wearing of appropriate safety equipment, such as lab gloves, goggles and lab clothes. This compound should be kept away from fire and heat. During use or storage, the compound should be kept in a sealed container, avoiding contact with oxygen, water or other incompatible substances.
Properties: 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole is a white solid. It has a molecular formula of C14H16BrNO3 and a molecular weight of 323.19g/mol. This compound is soluble in the solvent, but insoluble in water. Its melting point is 145-150 degrees Celsius. It is an organic compound containing in its structure the ring of indole and a carboxylic ester as well as a tert-butoxy group and a bromine atom.
Purpose: 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole has certain application potential in the pharmaceutical field and can be used as a pharmaceutical intermediate for the synthesis of biologically active compounds. Indole compounds have been widely used in drug research, with anti-inflammatory, anti-tumor and antibacterial activities.
Preparation method: 1-tert-butoxycarbonyl -6-bromo -3-ol -1H-indole can be obtained through a series of chemical reactions. First, indole is subjected to a substitution reaction with hydrobromic acid to give 6-bromoindole. The 6-bromoindole is then subjected to a condensation reaction with tert-butoxyhydroxyformate, catalyzed by a base, to yield 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole.
Safety information: Since 1-tert-butoxycarbonyl-6-bromo-3-ol-1H-indole is an organic compound, like all chemicals, it must be handled in a laboratory environment. The safe handling of chemicals must be strictly followed at the time of contact, including the wearing of appropriate safety equipment, such as lab gloves, goggles and lab clothes. This compound should be kept away from fire and heat. During use or storage, the compound should be kept in a sealed container, avoiding contact with oxygen, water or other incompatible substances.
Last Update：2024-04-09 21:04:16
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CAS: 114224-27-0
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CAS: 114224-27-0
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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