1143459-92-0
6-methyl-N1-(4-(pyridin-3-yl)thiazol-2-yl)benzene-1,3-diamine
CAS: 1143459-92-0
Molecular Formula: C15H14N4S.2(HCl)
1143459-92-0 - Names and Identifiers
1143459-92-0 - Physico-chemical Properties
| Molecular Formula | C15H14N4S.2(HCl) |
| Molar Mass | 355.28534 |
| Melting Point | 312-315 °C |
1143459-92-0 - Introduction
4-Methyl-N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine dihydrochloride is a compound with the chemical formula C15H16N6S · 2HCl, which has the following properties:
1. appearance: white to light yellow crystalline powder.
2. melting point: about 234-238 ℃.
3. Solubility: Soluble in water and alcohol, slightly soluble in ether and chloroform.
4. Stability: Stable at room temperature, but easy to decompose under light and heat conditions.
5. pH value: The pH value of the aqueous solution is stable in the range of 4.0-8.0.
The main uses of 4-Methyl-N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine dihydrochloride include:
1. Biomedicine: As an active ligand, it can be used in the fields of tumor treatment and image diagnosis.
2. field of organic synthesis: can be used as a ligand of metal catalyst, participate in the synthesis of organic compounds.
The compound can be obtained by the following preparation method:
1.4-(3-pyridyl)-1,3-phenylenediamine was obtained by reacting 4-methyl -1,3-phenylenediamine with 3-pyridinecarboxaldehyde;
2. reacting 4-(3-pyridyl)-1,3-phenylenediamine with 2-chlorothiazole to give 4-(3-pyridyl)-2-thiazolyl)-1,3-phenylenediamine;
3. reacting 4-(3-pyridyl)-2-thiazolyl)-1,3-phenylenediamine with nitrous acid to give N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine;
4. N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine is reacted with hydrochloric acid to give 4-methyl-N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine dihydrochloride.
Regarding safety information, due to the lack of specific experimental conditions and scope of use, please refer to relevant chemical safety manuals, technical materials or consult professional chemical suppliers for detailed safety information. Chemical experiments and the use of the compound should follow the relevant laboratory safety practices, and wear protective equipment.
1. appearance: white to light yellow crystalline powder.
2. melting point: about 234-238 ℃.
3. Solubility: Soluble in water and alcohol, slightly soluble in ether and chloroform.
4. Stability: Stable at room temperature, but easy to decompose under light and heat conditions.
5. pH value: The pH value of the aqueous solution is stable in the range of 4.0-8.0.
The main uses of 4-Methyl-N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine dihydrochloride include:
1. Biomedicine: As an active ligand, it can be used in the fields of tumor treatment and image diagnosis.
2. field of organic synthesis: can be used as a ligand of metal catalyst, participate in the synthesis of organic compounds.
The compound can be obtained by the following preparation method:
1.4-(3-pyridyl)-1,3-phenylenediamine was obtained by reacting 4-methyl -1,3-phenylenediamine with 3-pyridinecarboxaldehyde;
2. reacting 4-(3-pyridyl)-1,3-phenylenediamine with 2-chlorothiazole to give 4-(3-pyridyl)-2-thiazolyl)-1,3-phenylenediamine;
3. reacting 4-(3-pyridyl)-2-thiazolyl)-1,3-phenylenediamine with nitrous acid to give N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine;
4. N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine is reacted with hydrochloric acid to give 4-methyl-N3-[4-(3-pyridyl)-2-thiazolyl]-1,3-phenylenediamine dihydrochloride.
Regarding safety information, due to the lack of specific experimental conditions and scope of use, please refer to relevant chemical safety manuals, technical materials or consult professional chemical suppliers for detailed safety information. Chemical experiments and the use of the compound should follow the relevant laboratory safety practices, and wear protective equipment.
Last Update：2024-04-09 21:04:16
