114636-31-6

114636-31-6 - Names and Identifiers

Name	(3S)-(-)-3-Acetamidopyrrolidine
Synonyms	S-AAP (S)-3-Acetaminopyrrolidine (S)-3-ACETAMIDO-PYRROLIDINE (S)-(-)-3-ACETAMIDOPYRROLIDINE (3S)-(-)-3-Acetamidopyrrolidine (S)-N-PYRROLIDIN-3-YL-ACETAMIDE (3S)-(-)-3-ACETAMIDOPYRROLIDINE N-[(3R)-pyrrolidin-3-yl]acetaMide N-[(3S)-pyrrolidin-3-yl]acetamide N-[(3R)-pyrrolidin-3-yl]acetamide (S)-3-Acetaminopyrrolidine hydrochloride
CAS	114636-31-6
EINECS	631-217-4
InChI	InChI=1/C6H12N2O/c1-5(9)8-6-2-3-7-4-6/h6-7H,2-4H2,1H3,(H,8,9)/t6-/m0/s1

114636-31-6 - Physico-chemical Properties

Molecular Formula	C6H12N2O
Molar Mass	128.17
Density	1.04±0.1 g/cm3(Predicted)
Melting Point	56-58°C
Boling Point	70-72°C 40mm
Flash Point	70-72°C/40mm
Vapor Presure	0.000752mmHg at 25°C
Appearance	powder to crystal
Color	White to Orange to Green
BRN	4904139
pKa	15.94±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	-48 ° (C=1, EtOH)
MDL	MFCD00082748

114636-31-6 - Risk and Safety

Risk Codes	R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing.
UN IDs	3259
Hazard Class	8
Packing Group	III

114636-31-6 - Introduction

(3S)-(-)-3-Acetylaminotetrahydropyrrole is an organic compound with the following properties:

1. Appearance and Properties:(3S)-(-)-3-Acetylaminotetrahydropyrrole is a colorless to white crystalline solid.

2. Solubility: It is insoluble in water, but soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide.

3. Optical activity: It is a chiral compound with optical properties, and its optical rotation is negative.

The main uses of (3S)-(-)-3-acetylaminotetrahydropyrrole include:

1. Drug synthesis: It is an important intermediate for the synthesis of drugs, especially in the synthesis of implantable contraceptives, anti-inflammatory drugs and anti-Keshan disease drugs have a wide range of applications.

The preparation method of (3S)-(-)-3-acetylaminotetrahydropyrrole can be obtained by the following steps:

1. reacting tetrahydropyrrole with a compound having an acylating group to generate (3S)-(-)-3-acetylaminotetrahydropyrrole.

The safety information for (3S)-(-)-3-acetylaminotetrahydropyrrole is as follows:

1. fire and explosion hazard: the compound may burn or explode under the fire source.

2. Irritation and corrosiveness: It may cause irritation and corrosion to the eyes, respiratory system and skin.

3. toxic effects: untreated or incorrect use,(3S)-(-)-3-acetyl amino tetrahydropyrrole may have toxic effects on the human body. Therefore, it is necessary to pay attention to safe operation and strictly abide by the relevant safety operation procedures and protective measures.

Last Update：2024-04-09 20:48:19