114746-66-6

114746-66-6 - Names and Identifiers

Name	3-(Piperazin-1-ylmethyl)-1H-indole
Synonyms	3-(1-Piperazinylmethyl)indole 3-Piperazin-1-ylmethyl-1H-indole 3-(Piperazin-1-ylmethyl)-1H-indole 1H-Indole, 3-(1-piperazinylmethyl)-
CAS	114746-66-6
InChI	InChI=1/C13H17N3/c1-2-4-13-12(3-1)11(9-15-13)10-16-7-5-14-6-8-16/h1-4,9,14-15H,5-8,10H2

114746-66-6 - Physico-chemical Properties

Molecular Formula	C13H17N3
Molar Mass	215.29
Density	1.168±0.06 g/cm3(Predicted)
Boling Point	395.8±27.0 °C(Predicted)
Flash Point	193.2°C
Vapor Presure	1.79E-06mmHg at 25°C
Appearance	Solid
pKa	17.47±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.644

114746-66-6 - Introduction

3-(Piperazin-l-ylmethyl)-lH-indole is an organic compound with the chemical formula C13H12N2. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: 3-(piperazin-1-ylmethyl)-1H-indole is a white crystal or crystalline powder.
-Melting point: Its melting point range is 160-170°C.
-Solubility: It is almost insoluble in water, but can be dissolved in organic solvents.

Use:
-Drug synthesis: 3-(piperazin -1-ylmethyl)-1H-indole is commonly used as an intermediate in the synthesis of drugs, pesticides and dyes.

Method:
3-(piperazin-1-ylmethyl)-1H-indole is synthesized as follows:
1. First, benzaldehyde is reduced to benzyl alcohol by phenol.
2. Benzyl alcohol and 2-chloro-piperazine react under alkaline conditions to generate 3-(piperazin -1-ylmethyl)-1H-indole.

Safety Information:
-There is less toxicity and hazard data for 3-(piperazin -1-ylmethyl)-1H-indole, so appropriate laboratory safety measures should be taken when using or handling, and follow the relevant chemicals Operation manuals and regulations.
-May cause irritation to the eyes, skin, respiratory system and digestive system, so avoid contact and inhalation, and wear appropriate personal protective equipment (such as gloves, goggles, protective masks, etc.) when using.
-When using or disposing of, please take care to follow the environmental protection policy and take appropriate waste disposal measures.

Last Update：2024-04-09 21:01:54