1148118-92-6
Tripolin A
CAS: 1148118-92-6
Molecular Formula: C15H11NO3
1148118-92-6 - Names and Identifiers
1148118-92-6 - Physico-chemical Properties
| Molecular Formula | C15H11NO3 |
| Molar Mass | 253.25 |
| Density | 1.441±0.06 g/cm3(Predicted) |
| Melting Point | 265℃ (decomposition) |
| Boling Point | 584.9±50.0 °C(Predicted) |
| pKa | 9.66±0.48(Predicted) |
| Storage Condition | 2-8°C，密封，干燥 |
| In vitro study | Tripolin A induces mitotic spindle defects and spindle pole abnormalities. |
1148118-92-6 - Reference Information
| Biological activity | Tripolin A ((E)-Tripolin A) is a specific, non-ATP competitive Aurora A kinase inhibitor, and its IC50 for Aurora A and Aurora B are 1.5 μM and 7 μM respectively. |
| target | IC50: 1.5 μM (Aurora A), 7 μM (Aurora A). |
| in vitro study | Tripolin a induces mitotic spindle defects and spindle pole abnormalities. |
Last Update：2024-04-09 20:49:11
