114872-99-0

114872-99-0 - Names and Identifiers

Name	D-4-Trifluoromethylphe
Synonyms	H-D-PHE(4-CF 3)-OH RARECHEM BK PT 0142 H-D-Phe(4-CF3)-OH·HCl D-4-Trifluoromethylphe D-4-TRIFLUOROMETHYLPHE H-D-PHE(4-TRIFLUOROMETHYL)-OH D-4-TRIFLUOROMETHYLPHENYLALANINE D-4-Trifluoromethylphenylalanine 4-TRIFLUOROMETHYL-D-PHENYLALANINE 4-Trifluoromethyl-D-phenylalanine 4-(Trifluoromethyl)-D-Phenylalanine (2R)-2-ammonio-3-[4-(trifluoromethyl)phenyl]propanoate (R)-2-AMINO-3-(4-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID (2R)-2-amino-3-[4-(trifluoromethyl)phenyl]propanoic acid
CAS	114872-99-0
InChI	InChI=1/C10H10F3NO2/c11-10(12,13)7-3-1-6(2-4-7)5-8(14)9(15)16/h1-4,8H,5,14H2,(H,15,16)/t8-/m1/s1

114872-99-0 - Physico-chemical Properties

Molecular Formula	C10H10F3NO2
Molar Mass	233.19
Density	1.364±0.06 g/cm3(Predicted)
Boling Point	311.5±42.0 °C(Predicted)
Flash Point	142.2°C
Vapor Presure	0.00024mmHg at 25°C
pKa	2.15±0.10(Predicted)
Storage Condition	Store at -15°C
Refractive Index	1.502

114872-99-0 - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

114872-99-0 - Introduction

4-(Trifluoromethyl)-D-phenylalanine is an amino acid derivative with the following properties:
1. Appearance: White crystalline solid.
2. solubility: soluble in water.
3. Thermal stability: It has good stability at high temperature.

The main use of this compound is in the field of pharmaceutical synthesis. It is often used as an intermediate in the synthesis of drugs and can be used to synthesize organic compounds such as antibiotics and anticancer drugs.

The method for preparing 4-(trifluoromethyl)-D-phenylalanine generally includes the following steps:
1. Take 3-methoxystyrene as starting material.
2. The starting material is subjected to a series of chemical reactions, including substitution reaction, hydrogenation reaction, keto-alcohol interconversion, etc., and the target product 4-(trifluoromethyl)-D-phenylalanine is finally synthesized.

For safety information, 4-(trifluoromethyl)-D-phenylalanine is a chemical and the following should be noted:
1. Contact: Avoid direct contact with skin, eyes and respiratory tract.
2. inhalation: avoid inhalation of its dust or vapor solution.
3. ingestion: should avoid ingestion, such as eating should seek medical attention immediately.
4. storage: should be stored in a dry, cool, well-ventilated place, away from fire and possible oxidants.

It is recommended that the use or handling of this compound follow appropriate safety practices and comply with relevant regulations and guidelines.

Last Update：2024-04-09 20:02:46