115122-63-9 - Names and Identifiers
Name | 2-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carboxylic acid
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Synonyms | VITAS-BB TBB013110 TIMTEC-BB SBB010636 2-OXO-2,5,6,7-TETRAHYDRO-1H-[1]PYRINDINE-3-CARBOXYLIC ACID 2-hydroxy-5H,6H,7H-cyclopenta[b]pyridine-3-carboxylic acid 2-Hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carboxylicacid 2-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carboxylic acid 5H-cyclopenta[b]pyridine-3-carboxylic acid, 6,7-dihydro-2-hydroxy- 2,5,6,7-tetrahydro-2-oxo-1H-Cyclopenta[b]pyridine-3-carboxylic acid 2-Oxo-2,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carboxylic acid 2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carboxylic acid 1H-cyclopenta[b]pyridine-3-carboxylic acid, 2,5,6,7-tetrahydro-2-oxo-
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CAS | 115122-63-9
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InChI | InChI=1/C9H9NO3/c11-8-6(9(12)13)4-5-2-1-3-7(5)10-8/h4H,1-3H2,(H,10,11)(H,12,13) |
115122-63-9 - Physico-chemical Properties
Molecular Formula | C9H9NO3
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Molar Mass | 179.17 |
Density | 1.42±0.1 g/cm3(Predicted) |
Boling Point | 556.7±42.0 °C(Predicted) |
Flash Point | 224.441°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 3.05±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.661 |
115122-63-9 - Risk and Safety
115122-63-9 - Introduction
2-Hydroxy-6, 7-dihydro-5H-cyclopentane [B] pyridine-3-carboxylic acid, also known as saxaglitazone (saccharin), is an organic compound. The following is a description of the properties, uses, preparation and safety information of saxaglitazone:
Nature:
-Saglitazone is a white crystalline powder that is soluble in water and some organic solvents.
-It is an artificial sweetener with a sweet taste, and its sweetness is about 300-500 times that of sucrose.
-Stable under acidic conditions, but easily decomposed under alkaline conditions.
-saxaglitazone has the characteristics of good stability, high temperature resistance and difficult fermentation.
Use:
-Salxaglitazone is commonly used as a food additive to replace sugar to minimize the caloric content of foods.
-It is widely used in low-sugar or sugar-free foods, beverages, drugs and cosmetics.
-Saglitazone can also be used in the medical field as a therapeutic drug, for example, to prevent the increase of urine ketone bodies in diabetic patients.
Method:
-The preparation of saxaglitazone is generally carried out by the naphthalene diol method.
-The specific steps include preparing a precursor of saxaglitazone by reacting isocyanate and 2-oxocyclopentyl thiocyanate, and then converting the precursor into saxaglitazone by an oxidation reaction catalyzed by a base.
Safety Information:
-The use of saxaglitazone in food additives is considered safe, and many countries and regions have approved its use.
-Based on available scientific research, saxaglitazone has no significant side effects in most people, but individuals may experience its sweetness differently.
-Long-term intake of high doses may lead to a disorder in the perception of sweetness.
-For people who are allergic to saxaglitazone or have related contraindications, intake should be avoided. As an artificial sweetener, it should not be overused.
In general, saxaglitazone is a widely used food additive with sweet taste and good stability. In the case of moderate use, it can be used as a substitute for low-sugar or sugar-free products. However, in the use of the process should still pay attention to follow the relevant safety and health regulations.
Last Update:2024-04-09 20:45:29