116378-40-6

116378-40-6 - Names and Identifiers

Name	(3-Amino-5-carboxylphenyl)boronic acid
Synonyms	3-AMINO-5-BORONOBENZOIC ACID Benzoic acid, 3-aMino-5-borono 3-Amino-5-Carboxyphenylboronic Acid 3-Amino-5-carboxybenzeneboronic acid 3-AMINO-5-CARBOXYLPHENYLBORONIC ACID (3-AMINO-5-CARBOXYPHENYL)BORONIC ACID (3-Amino-5-carboxylphenyl)boronic acid 3-amino-5-(dihydroxyboranyl)benzoic acid
CAS	116378-40-6
InChI	InChI=1/C7H8BNO4/c9-6-2-4(7(10)11)1-5(3-6)8(12)13/h1-3,12-13H,9H2,(H,10,11)

116378-40-6 - Physico-chemical Properties

Molecular Formula	C7H8BNO4
Molar Mass	180.95
Density	1.49±0.1 g/cm3(Predicted)
Melting Point	210-212
Boling Point	545.5±60.0 °C(Predicted)
Flash Point	283.7°C
Vapor Presure	9.86E-13mmHg at 25°C
Appearance	Grey solid
pKa	3.35±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.63
MDL	MFCD02179466

116378-40-6 - Risk and Safety

Hazard Note

Harmful

116378-40-6 - Introduction

3-amino -5-carboxyphenylboronic acid is an organic compound with the chemical formula C7H7BO4N. The following is a description of its nature, use, preparation and safety information:

Nature:
-3-Amino-5-carboxyphenylboronic acid is a solid with a white or light yellow crystalline appearance.
-It is soluble in water and stable under acidic conditions.
-It is almost odorless in smell, but sometimes slightly bitter.
-It has certain thermal stability and can be stored and handled at higher temperatures.

Use:
-3-amino-5-carboxyphenylboronic acid can be used as a reagent and catalyst in organic synthesis reactions.
-It can participate in some important reactions, such as C- C bond formation reaction, hydroxylation reaction and oxidation reaction.
-It is widely used in the field of organic chemistry, especially in the preparation of drugs and pesticides, and has important application value.

Preparation Method:
The preparation of-3-amino-5-carboxyphenylboronic acid is usually carried out by chemical synthesis methods.
-A common preparation method is to react 3-aminobenzoic acid with certain oxidants (such as benzoyl peroxide) in the presence of boronic acid (NaBH4).

Safety Information:
-For the safety of 3-amino-5-carboxyphenylboronic acid, there is no clear toxicity data.
-However, as a chemical, use should follow the regular chemical laboratory procedures.
-recommend wear appropriate laboratory protective equipment, such as gloves and safety glasses, when in use.
-Avoid contact with skin and eyes, avoid inhaling aerosols of powders or solutions, and avoid ingestion.
-Care should be taken in handling and storage to prevent contact with incompatible substances, such as strong oxidants.

It should be noted that although the above information can be used as a reference in most cases, it is still recommended to refer to relevant reliable information and laboratory guidance for specific use and handling safety.

Last Update：2024-04-09 20:45:29