116734-22-6
2-(4-Methoxyphenyl)-6-methylquinoline-4-carboxylic acid
CAS: 116734-22-6
Molecular Formula: C18H15NO3
116734-22-6 - Names and Identifiers
116734-22-6 - Physico-chemical Properties
| Molecular Formula | C18H15NO3 |
| Molar Mass | 293.32 |
| Density | 1.248±0.06 g/cm3(Predicted) |
| Melting Point | 230-231 °C |
| Boling Point | 498.0±45.0 °C(Predicted) |
| pKa | 1.11±0.30(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD01825281 |
116734-22-6 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
116734-22-6 - Introduction
2-(4-Methoxyphenyl)-6-methylquinoline-4-carboxylic acid is an organic compound with the formula C18H15NO3.
Nature:
-Appearance: White solid
-Melting point: approx. 204-206°C
-Solubility: Slightly soluble in water, soluble in common organic solvents such as ethanol and chloroform
-chemical properties: esterification reaction can occur under acidic conditions, and substitution reaction and carbon oxidation reaction can also be carried out.
Use:
2-(4-Methoxyphenyl)-6-methylquinoline-4-carboxylic acid is an important pharmaceutical intermediate, commonly used in the synthesis of various drugs and bioactive molecules.
Preparation Method:
2-(4-Methoxyphenyl)-6-methylquinoline-4-carboxylic acid can be synthesized by a variety of methods. Common synthetic methods include:
-In the presence of 4-methoxyphenol and 2-methylquinoline, the oxidation reaction is carried out in an oxygen atmosphere to obtain the target product.
-The target product is obtained by the condensation reaction of 4-methoxyphenyl ethanone with 2-methylquinoline under alkaline conditions.
Safety Information:
Regarding the safety of 2-(4-methoxyphenyl)-6-methylquinoline-4-carboxylic acid, the relevant data are very limited and further research is needed. Appropriate safety precautions should be taken when using or handling the compound, such as wearing protective gloves, glasses and a mask, and avoiding inhalation, swallowing or contact with the skin. In the laboratory environment, should be in accordance with the laboratory safety operation procedures for operation. In the event of an accident, seek medical attention immediately.
Nature:
-Appearance: White solid
-Melting point: approx. 204-206°C
-Solubility: Slightly soluble in water, soluble in common organic solvents such as ethanol and chloroform
-chemical properties: esterification reaction can occur under acidic conditions, and substitution reaction and carbon oxidation reaction can also be carried out.
Use:
2-(4-Methoxyphenyl)-6-methylquinoline-4-carboxylic acid is an important pharmaceutical intermediate, commonly used in the synthesis of various drugs and bioactive molecules.
Preparation Method:
2-(4-Methoxyphenyl)-6-methylquinoline-4-carboxylic acid can be synthesized by a variety of methods. Common synthetic methods include:
-In the presence of 4-methoxyphenol and 2-methylquinoline, the oxidation reaction is carried out in an oxygen atmosphere to obtain the target product.
-The target product is obtained by the condensation reaction of 4-methoxyphenyl ethanone with 2-methylquinoline under alkaline conditions.
Safety Information:
Regarding the safety of 2-(4-methoxyphenyl)-6-methylquinoline-4-carboxylic acid, the relevant data are very limited and further research is needed. Appropriate safety precautions should be taken when using or handling the compound, such as wearing protective gloves, glasses and a mask, and avoiding inhalation, swallowing or contact with the skin. In the laboratory environment, should be in accordance with the laboratory safety operation procedures for operation. In the event of an accident, seek medical attention immediately.
Last Update：2024-04-09 21:54:55
