117106-21-5

117106-21-5 - Names and Identifiers

Name	Boc-Dab(Fmoc)-OH
Synonyms	Boc-Dab(Fmoc)-OH BOC-DAB(FMOC)-OH RARECHEM EM WB 0099 Boc-L-2,4-Diaminobutyric acid(Fmoc) BOC-ALPHA,GAMMA-DIAMINOBUTYRIC ACID(FMOC)-OH N-ALPHA-BOC-N-GAMMA-FMOC-L-DIAMINOBUTYRIC ACID N-ALPHA-BOC-N-GAMMA-FMOC-L-2,4-DIAMINOBUTYRIC ACID N-ALPHA-T-BUTYLOXYCARBONYL-N-BETA-9-FLUORENYLMETHYLOXYCARBONYL-L-2,4-DIAMINOBUTYRIC ACID (2S)-2-[(tert-butoxycarbonyl)amino]-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid N-ALPHA-TERT-BUTYLOXYCARBONYL-N-GAMMA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-2,4-DIAMINOBUTYRIC ACID N-ALPHA-T-BUTOXYCARBONYL-N-GAMMA-(9-FLUORENYLMETHOXYCARBONYL)-L-ALPHA,GAMMA-DIAMINOBUTYRIC ACID
CAS	117106-21-5
EINECS	1533716-785-6
InChI	InChI=1/C24H28N2O6/c1-24(2,3)32-23(30)26-20(21(27)28)12-13-25-22(29)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m0/s1

117106-21-5 - Physico-chemical Properties

Molecular Formula	C24H28N2O6
Molar Mass	440.49
Density	1.243±0.06 g/cm3(Predicted)
Melting Point	79-80 °C
Boling Point	670.9±55.0 °C(Predicted)
Flash Point	359.6°C
Vapor Presure	6.47E-19mmHg at 25°C
BRN	4771583
pKa	3.88±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.575

117106-21-5 - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
HS Code	29242990

117106-21-5 - Introduction

N-tert-butoxycarbonyl-N'-fluorenylmethoxycarbonyl-L-2, 4-diaminobutyric acid is a chemical compound, also known as Fmoc-L-Dab-OH. Its properties are as follows:

1. Appearance: white or almost white crystalline powder.
2. solubility: soluble in acid, alcohol and ketone solvents, more difficult to dissolve in water.
3. melting point: about 170-175 degrees Celsius.

N-tert-Butoxycarbonyl-N'-fluorenylmethoxycarbonyl-L-2, 4-diaminobutyric acid main uses include:
1. Used as a protecting group in polypeptide synthesis.
2. for the synthesis of biologically active peptides and proteins.

In the preparation method, N-tert-butoxycarbonyl-N'-fluorenylmethoxycarbonyl-L-2, 4-diaminobutyric acid can be synthesized by the following steps:
1. First, L-2, 4-diaminobutyric acid and carbon dioxide are reacted to obtain diaminobutyric acid ammonia carbamide.
2. Then, the reaction product is reacted with tert-butoxycarbonyl isocyanate and fluorenol to obtain N-tert-butoxycarbonyl-N'-fluorenylmethoxycarbonyl-L-2, 4-diaminobutyric acid.

Regarding safety information, under normal operation, N-tert-butoxycarbonyl-N'-fluorenylmethoxycarbonyl-L-2, 4-diaminobutyric acid is a relatively safe substance. However, as a chemical, it still needs to be disposed of properly. When in use, should follow the appropriate safety procedures, the use of personal protective equipment, avoid inhalation, contact with the skin and eyes. If you eat by mistake or have any discomfort symptoms, you should seek medical advice and bring a chemical label for reference.

Last Update：2024-04-09 21:48:26