1171775-66-8
4-(2,4-Difluorophenoxy)piperidine hydrochloride
CAS: 1171775-66-8
Molecular Formula: C11H14ClF2NO
1171775-66-8 - Names and Identifiers
| Name | 4-(2,4-Difluorophenoxy)piperidine hydrochloride |
| Synonyms | 4-(2,4-DIFLUOROPHENOXY)PIPERIDINE HYDROCHLORIDE 4-(2,4-Difluorophenoxy)piperidine hydrochloride |
| CAS | 1171775-66-8 |
1171775-66-8 - Physico-chemical Properties
| Molecular Formula | C11H14ClF2NO |
| Molar Mass | 249.6847664 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09997065 |
1171775-66-8 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
1171775-66-8 - Introduction
4-(2,4-Difluorophenoxy)piperidine hydrochloride is an organic compound with the chemical formula C11H14F2ClNO. It is a white solid, stable at room temperature.
This compound has many uses. It is a pharmaceutical intermediate commonly used in the synthesis of antipsychotics and antidepressants. It also has antibacterial activity and is used as an insecticide and fungicide in the agricultural field.
A method for preparing 4-(2,4-Difluorophenoxy)piperidine hydrochloride is generally obtained by reacting piperidine with 2,4-difluorophenol. Piperidine is first reacted with sodium hydroxide to give the corresponding piperidinophenol salt, which is then reacted with hydrogen fluoride to form 4-(2,4-difluorophenoxy) piperidine. Finally it is reacted with hydrochloric acid to give the hydrochloride form.
Regarding safety information, 4-(2,4-Difluorophenoxy)piperidine hydrochloride may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to pay attention to protective measures during use, such as wearing appropriate protective gloves, goggles and respiratory protection equipment. In addition, it should be kept away from fire sources and oxidants, and kept closed.
This compound has many uses. It is a pharmaceutical intermediate commonly used in the synthesis of antipsychotics and antidepressants. It also has antibacterial activity and is used as an insecticide and fungicide in the agricultural field.
A method for preparing 4-(2,4-Difluorophenoxy)piperidine hydrochloride is generally obtained by reacting piperidine with 2,4-difluorophenol. Piperidine is first reacted with sodium hydroxide to give the corresponding piperidinophenol salt, which is then reacted with hydrogen fluoride to form 4-(2,4-difluorophenoxy) piperidine. Finally it is reacted with hydrochloric acid to give the hydrochloride form.
Regarding safety information, 4-(2,4-Difluorophenoxy)piperidine hydrochloride may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to pay attention to protective measures during use, such as wearing appropriate protective gloves, goggles and respiratory protection equipment. In addition, it should be kept away from fire sources and oxidants, and kept closed.
Last Update：2024-04-09 20:52:54
