117528-59-3
3-Cyano-2,4-dichloro-5-fluorobenzoylchloride
CAS: 117528-59-3
Molecular Formula: C8HCl3FNO
117528-59-3 - Names and Identifiers
117528-59-3 - Physico-chemical Properties
| Molecular Formula | C8HCl3FNO |
| Molar Mass | 252.46 |
| Density | 1.66±0.1 g/cm3(Predicted) |
| Melting Point | 69-72℃ |
| Boling Point | 333.9±42.0 °C(Predicted) |
117528-59-3 - Risk and Safety
| Risk Codes | R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 3261 |
117528-59-3 - Introduction
3-Cyano-2, 4-dichloro-5-fluorobenzoyl chloride is an organic compound with the chemical formula C7H2Cl2FNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-cyano-2, 4-dichloro-5-fluorobenzoyl chloride is a colorless to yellow liquid.
-Melting point:-5 ℃
-Boiling point: 65-66 ℃
-Density: 1.62g/cm³
-Solubility: It is soluble in most organic solvents, but insoluble in water.
Use:
- 3-cyano -2,4-dichloro -5-fluorobenzoyl chloride is a pesticide and insecticide intermediates, commonly used in the synthesis of highly effective insecticides such as fumaryl fluoride. It has strong insecticidal activity and is effective against a variety of pests.
Preparation Method:
- 3-cyanide -2, 4-dichloro-5-fluorobenzoyl chloride preparation method is more complex, generally involving a number of organic synthesis steps. Here is one possible synthetic route:
1.3-Cyano-2, 4-dichlorobenzoic acid is obtained by reacting 3-cyanobenzoic acid with dichloromethane.
2.3-cyano -2,4-dichlorobenzoic acid is reacted with sodium sulfite to obtain 3-cyano -2,4-dichloro -5-sulfuryl benzoic acid.
3.3-cyano -2,4-dichloro -5-sulfoacyl benzoic acid is reacted with antimony trifluoride to obtain 3-cyano -2,4-dichloro -5-fluorobenzoic acid.
4. Finally, 3-cyano-2, 4-dichloro-5-fluorobenzoyl chloride was obtained by acylchloride treatment.
Safety Information:
-3-cyano-2, 4-dichloro-5-fluorobenzoyl chloride is an organic synthesis intermediate with certain toxicity.
-Appropriate protective equipment such as gloves, goggles and gas masks are required for operation.
-Avoid breathing its vapors and contact with skin.
-Pay attention to the fire source during use and ensure good ventilation.
-should be stored in a dry, cool place, and away from acids, alkalis and oxidants and other substances.
-Observe local regulations when disposing of waste.
Nature:
-Appearance: 3-cyano-2, 4-dichloro-5-fluorobenzoyl chloride is a colorless to yellow liquid.
-Melting point:-5 ℃
-Boiling point: 65-66 ℃
-Density: 1.62g/cm³
-Solubility: It is soluble in most organic solvents, but insoluble in water.
Use:
- 3-cyano -2,4-dichloro -5-fluorobenzoyl chloride is a pesticide and insecticide intermediates, commonly used in the synthesis of highly effective insecticides such as fumaryl fluoride. It has strong insecticidal activity and is effective against a variety of pests.
Preparation Method:
- 3-cyanide -2, 4-dichloro-5-fluorobenzoyl chloride preparation method is more complex, generally involving a number of organic synthesis steps. Here is one possible synthetic route:
1.3-Cyano-2, 4-dichlorobenzoic acid is obtained by reacting 3-cyanobenzoic acid with dichloromethane.
2.3-cyano -2,4-dichlorobenzoic acid is reacted with sodium sulfite to obtain 3-cyano -2,4-dichloro -5-sulfuryl benzoic acid.
3.3-cyano -2,4-dichloro -5-sulfoacyl benzoic acid is reacted with antimony trifluoride to obtain 3-cyano -2,4-dichloro -5-fluorobenzoic acid.
4. Finally, 3-cyano-2, 4-dichloro-5-fluorobenzoyl chloride was obtained by acylchloride treatment.
Safety Information:
-3-cyano-2, 4-dichloro-5-fluorobenzoyl chloride is an organic synthesis intermediate with certain toxicity.
-Appropriate protective equipment such as gloves, goggles and gas masks are required for operation.
-Avoid breathing its vapors and contact with skin.
-Pay attention to the fire source during use and ensure good ventilation.
-should be stored in a dry, cool place, and away from acids, alkalis and oxidants and other substances.
-Observe local regulations when disposing of waste.
Last Update：2024-04-10 22:29:15
