1177318-36-3
5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol
CAS: 1177318-36-3
Molecular Formula: C8H10Cl2N2O2
1177318-36-3 - Names and Identifiers
1177318-36-3 - Physico-chemical Properties
| Molecular Formula | C8H10Cl2N2O2 |
| Molar Mass | 237.08 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD04140657 |
1177318-36-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
1177318-36-3 - Introduction
5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol, chemical formula C9H8ClN3OS, known as 5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol), is an organic compound with a specific structure.
Nature:
-Appearance: A white solid powder
-Melting point: about 180-183°C
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide and dichloromethane, slightly soluble in water
Use:
5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol has certain applications in agriculture and medicine:
-Pesticide: It can be used as a fungicide, widely used in pesticide control of rice, wheat, grapes, cotton and other crops, and has a good control effect on some pathogenic fungi.
-Medicine: It is also used to prepare some specific pharmaceutical active compounds, such as anti-tumor drugs and anti-inflammatory drugs.
Preparation Method:
The preparation of 5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol is generally carried out by the following steps:
1. ammonium sulfate and formic acid are heated in an appropriate solvent to react to generate thiourea (4-methyl-1,2,4-triazole-3-thiol).
2. under alkaline conditions, the reaction of methyl thiourea and chlorophenyl methyl ether generates [(2-chloro-5-nitrophenyl) methyl] thiourea.
3. The generated [(2-chloro-5-nitrophenyl) methyl] thiourea is reacted with methylamine hydrochloride to generate the target product.
Safety Information:
5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol is relatively safe for the human body when used and stored correctly. However, as a chemical, it still has some potential hazards and toxicity, and should be used in accordance with relevant safety procedures and avoid contact with skin, eyes and respiratory tract. In the use of the process should follow the relevant safety procedures, avoid inhalation of dust, and pay attention to the safety of storage, disposal.
Nature:
-Appearance: A white solid powder
-Melting point: about 180-183°C
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide and dichloromethane, slightly soluble in water
Use:
5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol has certain applications in agriculture and medicine:
-Pesticide: It can be used as a fungicide, widely used in pesticide control of rice, wheat, grapes, cotton and other crops, and has a good control effect on some pathogenic fungi.
-Medicine: It is also used to prepare some specific pharmaceutical active compounds, such as anti-tumor drugs and anti-inflammatory drugs.
Preparation Method:
The preparation of 5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol is generally carried out by the following steps:
1. ammonium sulfate and formic acid are heated in an appropriate solvent to react to generate thiourea (4-methyl-1,2,4-triazole-3-thiol).
2. under alkaline conditions, the reaction of methyl thiourea and chlorophenyl methyl ether generates [(2-chloro-5-nitrophenyl) methyl] thiourea.
3. The generated [(2-chloro-5-nitrophenyl) methyl] thiourea is reacted with methylamine hydrochloride to generate the target product.
Safety Information:
5-[(2-Chlorophenoxy)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol is relatively safe for the human body when used and stored correctly. However, as a chemical, it still has some potential hazards and toxicity, and should be used in accordance with relevant safety procedures and avoid contact with skin, eyes and respiratory tract. In the use of the process should follow the relevant safety procedures, avoid inhalation of dust, and pay attention to the safety of storage, disposal.
Last Update：2024-04-09 20:45:29
