117903-25-0
BOC-MENLE-OH
CAS: 117903-25-0
Molecular Formula: C12H23NO4
117903-25-0 - Names and Identifiers
| Name | BOC-MENLE-OH |
| Synonyms | BOC-MENLE-OH BOC-L-MENLE-OH BOC-N-ME-NLE-OH BOC-MEAHX(2)-OH BOC-MEACPO(2)-OH BOC-N-ME-NORLEUCINE Boc-N-methyl-L-norleucine BOC-N-ALPHA-METHYL-L-NORLEUCINE BOC-N-ME-L-2-AMINOHEXANOIC ACID N-(tert-butoxycarbonyl)-N-methyl-L-norleucine |
| CAS | 117903-25-0 |
| InChI | InChI=1/C12H23NO4/c1-6-7-8-9(10(14)15)13(5)11(16)17-12(2,3)4/h9H,6-8H2,1-5H3,(H,14,15)/t9-/m0/s1 |
117903-25-0 - Physico-chemical Properties
| Molecular Formula | C12H23NO4 |
| Molar Mass | 245.32 |
| Density | 1.055±0.06 g/cm3(Predicted) |
| Boling Point | 343.6±21.0 °C(Predicted) |
| Flash Point | 161.6°C |
| Vapor Presure | 1.25E-05mmHg at 25°C |
| pKa | 4.03±0.21(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.468 |
| Physical and Chemical Properties | Storage Conditions: Store at 0-5 ℃ WGK Germany:3 |
117903-25-0 - Risk and Safety
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
117903-25-0 - Introduction
N-tert-butoxycarbonyl-N-methyl-L-norleucine is a compound also known as Boc-L-norleucine methyl ester. The following is a description of its nature, use, formulation and safety information:
Nature:
N-tert-Butoxycarbonyl-N-methyl-L-norleucine is a white solid with low toxicity. It is stable at room temperature, but reacts with strong oxidants.
Use:
Boc-L-norleucine methyl ester is widely used in organic synthesis. It is generally used as a protecting group in peptide synthesis, which can protect the amino group to avoid accidental amino reaction in the reaction. In addition, it can also be used to prepare drugs, pesticides and biologically active small molecules.
Preparation Method:
N-tert-butoxycarbonyl-N-methyl-L-norleucine is generally prepared by reacting tert-butoxycarbonyl chloride with L-norleucine methyl ester. The reaction is usually carried out at a low temperature, and an anhydrous solvent or an organic solvent such as dichloromethane, dimethylformamide and the like is used.
Safety Information:
Although Boc-L-norleucine methyl ester is relatively safe when used under general laboratory conditions, it is still a chemical and requires proper handling. Avoid inhalation, contact with skin and eyes, and store in a dry, well-ventilated place. Personal protective equipment such as goggles, gloves and laboratory coats should be worn during use. In the process of operation, attention should be paid to follow the safety procedures and avoid contact with oxidants and other hazardous chemicals. In the event of an accident, immediately flush the affected area with plenty of water and seek medical help.
Nature:
N-tert-Butoxycarbonyl-N-methyl-L-norleucine is a white solid with low toxicity. It is stable at room temperature, but reacts with strong oxidants.
Use:
Boc-L-norleucine methyl ester is widely used in organic synthesis. It is generally used as a protecting group in peptide synthesis, which can protect the amino group to avoid accidental amino reaction in the reaction. In addition, it can also be used to prepare drugs, pesticides and biologically active small molecules.
Preparation Method:
N-tert-butoxycarbonyl-N-methyl-L-norleucine is generally prepared by reacting tert-butoxycarbonyl chloride with L-norleucine methyl ester. The reaction is usually carried out at a low temperature, and an anhydrous solvent or an organic solvent such as dichloromethane, dimethylformamide and the like is used.
Safety Information:
Although Boc-L-norleucine methyl ester is relatively safe when used under general laboratory conditions, it is still a chemical and requires proper handling. Avoid inhalation, contact with skin and eyes, and store in a dry, well-ventilated place. Personal protective equipment such as goggles, gloves and laboratory coats should be worn during use. In the process of operation, attention should be paid to follow the safety procedures and avoid contact with oxidants and other hazardous chemicals. In the event of an accident, immediately flush the affected area with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:51
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