1185303-48-3
2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride
CAS: 1185303-48-3
Molecular Formula: C13H19Cl2N3O
1185303-48-3 - Names and Identifiers
1185303-48-3 - Physico-chemical Properties
| Molecular Formula | C13H19Cl2N3O |
| Molar Mass | 304.22 |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD06800433 |
1185303-48-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
1185303-48-3 - Introduction
2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride (2-chloro-N-[4-(4-methylpiperazin-1-yl)-phenyl]-acetamide hydrochloride) is an organic compound. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Chemical formula: C15H21Cl2N3O
-Molecular weight: 338.25g/mol
-Appearance: White or off-white crystalline powder
-Melting point: 182-186°C
-Solubility: Poor solubility in water, better solubility in some organic solvents (such as ethanol, chloroform)
-Stability: stable under dry conditions, and should avoid light
Use:
- 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride has certain uses in the field of medicine, and is often used as an intermediate for antipsychotic drugs or antidepressant drugs.
-It is also used as an important intermediate in the synthesis of some chemical reagents, such as organic synthesis.
Preparation Method:
The preparation method of 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-acetamide hydrochloride can be carried out by the following steps:
1. alkylation of 4-methyl piperazine with chloroacetic acid to generate methyl 4-(4-methyl piperazin -1-yl) acetate.
2. Acylation of the product obtained in step 1 with 2-chloroacetyl chloride in an appropriate solvent to generate 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide.
3. Hydrochloric acid salification reaction is performed on the product obtained in step 2 using hydrogen chloride and aqueous hydrochloric acid solution to generate 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride.
Safety Information:
- 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride can be kept safe under correct use and handling.
-Appropriate protective measures should be taken during operation, such as wearing protective glasses, gloves and laboratory clothing.
-Avoid inhalation, ingestion, or skin contact with the compound.
-If inhalation, ingestion or skin contact occurs, rinse immediately with plenty of water and seek medical assistance.
Please note that 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride is a chemical substance. Ensure that it is used in accordance with safe operating procedures and consult professional guidance.
Nature:
-Chemical formula: C15H21Cl2N3O
-Molecular weight: 338.25g/mol
-Appearance: White or off-white crystalline powder
-Melting point: 182-186°C
-Solubility: Poor solubility in water, better solubility in some organic solvents (such as ethanol, chloroform)
-Stability: stable under dry conditions, and should avoid light
Use:
- 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride has certain uses in the field of medicine, and is often used as an intermediate for antipsychotic drugs or antidepressant drugs.
-It is also used as an important intermediate in the synthesis of some chemical reagents, such as organic synthesis.
Preparation Method:
The preparation method of 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-acetamide hydrochloride can be carried out by the following steps:
1. alkylation of 4-methyl piperazine with chloroacetic acid to generate methyl 4-(4-methyl piperazin -1-yl) acetate.
2. Acylation of the product obtained in step 1 with 2-chloroacetyl chloride in an appropriate solvent to generate 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide.
3. Hydrochloric acid salification reaction is performed on the product obtained in step 2 using hydrogen chloride and aqueous hydrochloric acid solution to generate 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride.
Safety Information:
- 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride can be kept safe under correct use and handling.
-Appropriate protective measures should be taken during operation, such as wearing protective glasses, gloves and laboratory clothing.
-Avoid inhalation, ingestion, or skin contact with the compound.
-If inhalation, ingestion or skin contact occurs, rinse immediately with plenty of water and seek medical assistance.
Please note that 2-Chloro-N-[4-(4-methyl-piperazin-1-yl)-phenyl]-acetamide hydrochloride is a chemical substance. Ensure that it is used in accordance with safe operating procedures and consult professional guidance.
Last Update：2024-04-09 15:18:10
