1189561-66-7

Molecular Formula	C32H34O10
Molar Mass	578.61
Solubility	10 mM in DMSO
Storage Condition	-20℃
In vitro study	The natural racemic Gossypol has two enantiomers, namely the (-)-Gossypol and (S)-Gossypol ((+)-Gossypol) enantiomers. (+)-Gossypol and (-)-Gossypol binds to Bcl-2 or Bcl-xL with similar binding affinities. (-)-Gossypol is more potent than (+)-Gossypol in inhibition of cell growth and induction of apoptosis. The racemic form and each of the enantiomers of Gossypol are tested against UM-SCC-6 and UM-SCC-14A in 6-day MTT assays. (-)-Gossypol exhibits greater growth inhibition relative to (±)-Gossypol than (+)-Gossypol in both cell lines tested (P<0.001). An intermediate growth inhibitory effect is observed with (±)-Gossypol but this effect is only observed at the higher dose of Gossypol (10 μM, P<0.0001).

Last Update：2024-01-02 23:10:35

Product Name: (S)-Gossypol (acetic acid) Visit Supplier Webpage Request for quotation
CAS: 1189561-66-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: (S)-Gossypol (acetic acid) Visit Supplier Webpage Request for quotation
CAS: 1189561-66-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

1189561-66-7

1189561-66-7 Request for Quotation