1189888-77-4 - Names and Identifiers
1189888-77-4 - Physico-chemical Properties
Molecular Formula | C17H17ClN4
|
Molar Mass | 312.8 |
Storage Condition | -20°C |
1189888-77-4 - Introduction
N-Desmethyl Clozapine-d8 (n-desmethylclozapin-d8) is a labeled compound with the following properties, uses, preparation methods and safety information:
1. Properties: N-Desmethyl Clozapine-d8 is a derivative of clozapine, which has the removal of hydrogen atoms (H) and the substitution of deuterium (D), therefore, 8 hydrogen atoms in the molecule are replaced by deuterium atoms. This compound is clozapine with a stable isotope.
2. Purpose: N-Desmethyl Clozapine-d8 is mainly used in pharmacokinetics and drug metabolism research. It can be used as a substrate for drug-metabolizing enzymes (such as cytochrome P450 enzymes) to study the metabolic pathways of drugs in the body, the formation of metabolites, etc.
3. Preparation method: N-Desmethyl Clozapine-d8 are usually prepared by synthetic chemical methods. A particular preparation may involve reacting clozapine with a diazo compound, followed by further treatment to obtain the desired labeled compound.
4. Safety Information: Studies on toxicity and safety of N-Desmethyl Clozapine-d8 are relatively limited and require careful handling. In the use of the process should follow the laboratory practice and personal protective measures, such as wearing gloves, laboratory goggles, etc. According to the laboratory's chemical waste treatment regulations, the waste should be properly disposed.
Please note that when using or handling chemical substances, you should follow the relevant safety operation guidelines and regulations, and evaluate and take corresponding protective measures according to the actual situation.
Last Update:2024-04-09 20:49:11