1194-21-4

1194-21-4 - Names and Identifiers

Name	2-Amino-6-chloro-4-pyrimidinol
Synonyms	AKOS 92811 2-AMINO-4-CHLORO-6-PYRIMIDINOL 2-AMino-6-chloropyriMidin-4-ol 2-Amino-6-chloro-4-pyrimidinol 2-amino-6-chloropyrimidin-4(3H)-one 2-aMino-6-chloropyriMidine-4,5-diol 2-AMINO-4-HYDROXY-6-CHLOROPYRIMIDINE 2-AMINO-6-CHLORO-4-HYDROXYPYRIMIDINE 2-Amino-4-chloro-6-hydroxypyrimidine 2-AMINO-4-CHLORO-6-HYDROXYPYRIMIDINE 2-amino-6-chloropyrimidin-4-ol hydrate 2-Amino-6-chloro-4-pyrimidinol hydrate 2-AMino-6-Chloro-4-PyriMidinol Monohydr 2-Amino-6-chloro-4-pyrimidinol monohydrate
CAS	1194-21-4
EINECS	214-785-4
InChI	InChI=1/C4H4ClN3O/c5-2-1-3(9)8-4(6)7-2/h1H2,(H2,6,8,9)

1194-21-4 - Physico-chemical Properties

Molecular Formula	C4H4ClN3O
Molar Mass	145.55
Density	1.7910 (rough estimate)
Melting Point	252°C (dec.)(lit.)
Boling Point	259.1±50.0 °C(Predicted)
Flash Point	117.5°C
Solubility	DMSO (Sparingly)
Vapor Presure	0.00676mmHg at 25°C
Appearance	Solid
Color	Pale Yellow
pKa	7.49±0.50(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Stability	Hygroscopic
Refractive Index	1.4510 (estimate)
MDL	MFCD00006093

1194-21-4 - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
RTECS	UW5995000
HS Code	29335990

1194-21-4 - Introduction

2-Amino-6-chloro-4-hydroxypyrimidine (2-) is an organic compound with the chemical formula C4H4ClN3O. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: Colorless or light yellow crystal
-Melting point: 226-228°C
-Solubility: Slightly soluble in water, soluble in most organic solvents

Use:
-chemical reagents: in organic synthesis can be used as reagents, intermediates or catalyst raw materials.
-drugs: can be used for the synthesis of anti-cancer drugs, antiviral drugs.

Preparation Method:
There are many ways to prepare 2-amino-6-chloro-4-hydroxypyrimidine. A common preparation method is through the hydrogenation and reduction of 3-amino-5-chloro-2, 4(1H,3H)-Pyrimidine dione, or through the synthesis of 2-amino-6-chloro-4-hydroxypyrimidine under appropriate conditions.

Safety Information:
- 2-amino -6-chloro -4-hydroxyl pyrimidine is irritating to the skin and eyes, and protective measures should be paid attention to when using.
-Avoid reaction with oxidants or strong acids during operation and storage to prevent hazardous substances.
-When using and handling this compound, you should follow safe operating methods, pay attention to personal protection and ventilation protection.

Last Update：2024-04-09 02:00:41