1196-38-9

1196-38-9 - Names and Identifiers

Name	3,4-Dihydro-2H-isoquinolin-1-one
Synonyms	CHEMPACIFIC 43808 3,4-dihydroisoquinolin-1-ol 3,4-Dihydro-1-isoquinolinone 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE 3,4-Dihydro-2H-isoquinolin-1-one 3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 3,4-DIHYDRO-1(2H)-ISOQUINOLINONE 1(2H)-Isoquinolinone, 3,4-dihydro- 1-oxo-1,2,3,4-tetrahydroisoquinoline
CAS	1196-38-9
InChI	InChI=1/C9H9NO/c11-9-8-4-2-1-3-7(8)5-6-10-9/h1-4H,5-6H2,(H,10,11)

1196-38-9 - Physico-chemical Properties

Molecular Formula	C9H9NO
Molar Mass	147.17
Density	1.142
Melting Point	166 °C
Boling Point	138-143 °C(Press: 0.3 Torr)
Flash Point	226.5°C
Vapor Presure	3.14E-06mmHg at 25°C
Appearance	White solid
pKa	14.56±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.564
MDL	MFCD00853963

1196-38-9 - Introduction

3,4-Dihydroisoquinolinone -1(2H)-one, also known as dihydroquinolinone, is an organic compound. Its molecular formula is C9H9NO and it has two hydrogen atoms and one oxygen atom.

Nature:
3,4-Dihydroisoquinolin-1 (2H)-one is a colorless crystal and can be dissolved in organic solvents. It is weakly alkaline and does not dissolve in water. The compound is stable at room temperature.

Use:
3,4-Dihydroisoquinoline -1(2H)-one is commonly used as an intermediate in the synthesis of drugs. It can be used to synthesize biologically active compounds, such as antibacterial agents, anticancer drugs, etc.

Preparation Method:
A common synthetic method is starting from 3,4-dihydroquinoline starting material. First, 3,4-dihydroquinoline is reacted with an acid chloride by a synthetic reaction to produce the corresponding acylated product. The oxidized product is then reduced to 3,4-dihydroisoquinolin-1 (2H)-one by a reduction reaction.

Safety Information:
There are no clear data on the toxicity and safety of 3,4-dihydroisoquinolin-1 (2H)-one. However, as an organic compound used in the laboratory, necessary safety measures need to be taken, such as wearing protective gloves, goggles and protective clothing. Any chemical should follow safe practices and be evaluated at all times on the basis of relevant information.

Last Update：2024-04-09 21:01:54