1197996-80-7
1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)
CAS: 1197996-80-7
Molecular Formula: C21H24N2O2
1197996-80-7 - Names and Identifiers
| Name | 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) |
| Synonyms | CBL0137 Curaxin CURAXIN CBL-0137 CBLC 137 CBL-0137 CBL 0137 Curaxin 137 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) Ethanone, 1,1'-[9-[2-[(1-methylethyl)amino]ethyl]-9H-carbazole-3,6-diyl]bis- |
| CAS | 1197996-80-7 |
1197996-80-7 - Physico-chemical Properties
| Molecular Formula | C21H24N2O2 |
| Molar Mass | 336.43 |
| Solubility | Dissolved in DMSO |
| Storage Condition | -20°C |
1197996-80-7 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.973 ml | 14.863 ml | 29.727 ml |
| 5 mM | 0.595 ml | 2.973 ml | 5.945 ml |
| 10 mM | 0.297 ml | 1.486 ml | 2.973 ml |
| 5 mM | 0.059 ml | 0.297 ml | 0.595 ml |
Last Update：2024-01-02 23:10:35
1197996-80-7 - Reference Information
| biological activity | CBL0137 (Curaxin-137) is an inhibitor of histone chaperone FACT (facilitates chromatin transcription), which can inhibit NF-κB and activate p53 at the same time, with corresponding EC50 values of 0.47 μM and 0.37 μM respectively. |
| target | TargetValue FACT () p53 (Cell-free say) 0.37 μM(EC50) NF-κB (Cell-free say) 0.47 μM(EC50) |
| Target | Value |
| FACT () | |
| p53 (Cell-free assay) | 0.37 μM(EC50) |
| NF-κB (Cell-free assay) | 0.47 μM(EC50) |
Last Update：2024-04-09 15:16:37
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Spot supply
Product Name: 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) Visit Supplier Webpage Request for quotationCAS: 1197996-80-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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