1199215-81-0
5-Bromo-3-cyclobutyl-1H-1,2,4-triazole
CAS: 1199215-81-0
Molecular Formula: C6H8BrN3
1199215-81-0 - Names and Identifiers
| Name | 5-Bromo-3-cyclobutyl-1H-1,2,4-triazole |
| Synonyms | 5-Bromo-3-cyclobutyl-1H-1,2,4-triazole |
| CAS | 1199215-81-0 |
1199215-81-0 - Physico-chemical Properties
| Molecular Formula | C6H8BrN3 |
| Molar Mass | 202.05 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD13188620 |
1199215-81-0 - Risk and Safety
| Hazard Class | IRRITANT |
1199215-81-0 - Introduction
5-Bromo-3-cyclobutyl-1H-1,2,4-triazole (5-bromo-3-cyclobutyl-1H-1, 2,4-triazole) is an organic compound. The following is a description of some of its properties, uses, methods and safety information:
Nature:
-Appearance: White to light yellow crystalline solid.
-Molecular formula: C7H10BrN3.
-Molecular weight: 215.08g/mol.
-Melting point: about 78-82°C.
-Solubility: Soluble in common organic solvents.
Use:
-5-Bromo-3-cyloputyl-1H-1, 2,4-triazole is an important active intermediate for the synthesis of pesticides, pharmaceuticals and other organic compounds.
-Its application in the field of medicine includes anti-tumor drugs, antibacterial drugs, etc.
Preparation Method:
The synthesis method of 5-Bromo-3-cyclobutyl-1H-1,2,4-triazole can be carried out by the following steps:
1. The specific preparation method can be adjusted according to the reaction conditions and the required yield. Only a reference scheme is provided below.
2.2-amino -4-bromopyridine and cyclobutyl acetone are condensed by an organic acid to generate 2-(1,3-cyclobutanediyl) pyridine.
3.2-(1,3-cyclobutanediyl) pyridine is reacted with bromoacetone in the presence of a base to generate 5-bromo-3-cyclobutyl-1H-1, 2,4-triazole.
Safety Information:
- 5-Bromo-3-cyclobutyl-1H-1,2,4-triazole should be used in accordance with appropriate laboratory safety procedures.
-When in contact with skin, eyes or after taking, should immediately rinse the relevant parts with plenty of water.
-When storing, please store it in a dry, cool and ventilated place, away from fire and oxidizing agents.
-Avoid inhaling dust or gas during handling.
-Please refer carefully to the relevant safety data form and consult with the chemical supplier or professional before use.
Nature:
-Appearance: White to light yellow crystalline solid.
-Molecular formula: C7H10BrN3.
-Molecular weight: 215.08g/mol.
-Melting point: about 78-82°C.
-Solubility: Soluble in common organic solvents.
Use:
-5-Bromo-3-cyloputyl-1H-1, 2,4-triazole is an important active intermediate for the synthesis of pesticides, pharmaceuticals and other organic compounds.
-Its application in the field of medicine includes anti-tumor drugs, antibacterial drugs, etc.
Preparation Method:
The synthesis method of 5-Bromo-3-cyclobutyl-1H-1,2,4-triazole can be carried out by the following steps:
1. The specific preparation method can be adjusted according to the reaction conditions and the required yield. Only a reference scheme is provided below.
2.2-amino -4-bromopyridine and cyclobutyl acetone are condensed by an organic acid to generate 2-(1,3-cyclobutanediyl) pyridine.
3.2-(1,3-cyclobutanediyl) pyridine is reacted with bromoacetone in the presence of a base to generate 5-bromo-3-cyclobutyl-1H-1, 2,4-triazole.
Safety Information:
- 5-Bromo-3-cyclobutyl-1H-1,2,4-triazole should be used in accordance with appropriate laboratory safety procedures.
-When in contact with skin, eyes or after taking, should immediately rinse the relevant parts with plenty of water.
-When storing, please store it in a dry, cool and ventilated place, away from fire and oxidizing agents.
-Avoid inhaling dust or gas during handling.
-Please refer carefully to the relevant safety data form and consult with the chemical supplier or professional before use.
Last Update：2024-04-09 02:00:56
