120075-24-3
N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine
CAS: 120075-24-3
Molecular Formula: C31H36N4O7S
120075-24-3 - Names and Identifiers
120075-24-3 - Physico-chemical Properties
| Molecular Formula | C31H36N4O7S |
| Molar Mass | 608.71 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Appearance | Solid |
| pKa | 3.83±0.21(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.634 |
| Physical and Chemical Properties | Storage Conditions: 2-8C WGK Germany:- |
120075-24-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | - |
| Hazard Class | IRRITANT |
120075-24-3 - Introduction
N-Fmoc-N '-(4-methoxy-2, 3,6-trimethylbenzenesulfonyl)-D-arginine is an organic compound with the molecular formula C35H41N5O7S and a relative molecular mass of 679.8g/mol.
This compound is commonly used as a protecting group in peptide synthesis, which is attached to the amino terminal to protect and stabilize the amino acid. In the peptide synthesis reaction, it can promote the reaction of the N-alpha hydroxyl group by the amino activator to prevent the coupling to deprotected amino acid. It can also restore the original properties of D-arginine by removing the protecting group.
The method of preparing this compound is generally by reacting N-Fmoc-D-arginine with 2,3, 6-trimethylbenzenesulfonyl chloride in methanol, and then treating with a base to remove the protecting group.
Regarding safety information, N-Fmoc-N '-(4-methoxy-2, 3,6-trimethylbenzenesulfonyl)-D-arginine is a chemical and should be used in accordance with safe operating procedures. It may be irritating to the eyes, skin and respiratory system and direct contact should be avoided. Wear appropriate personal protective equipment such as lab gloves, safety glasses and protective masks during use. In storage should be placed in a dry, cool place, away from the fire source and may cause fire substances.
This compound is commonly used as a protecting group in peptide synthesis, which is attached to the amino terminal to protect and stabilize the amino acid. In the peptide synthesis reaction, it can promote the reaction of the N-alpha hydroxyl group by the amino activator to prevent the coupling to deprotected amino acid. It can also restore the original properties of D-arginine by removing the protecting group.
The method of preparing this compound is generally by reacting N-Fmoc-D-arginine with 2,3, 6-trimethylbenzenesulfonyl chloride in methanol, and then treating with a base to remove the protecting group.
Regarding safety information, N-Fmoc-N '-(4-methoxy-2, 3,6-trimethylbenzenesulfonyl)-D-arginine is a chemical and should be used in accordance with safe operating procedures. It may be irritating to the eyes, skin and respiratory system and direct contact should be avoided. Wear appropriate personal protective equipment such as lab gloves, safety glasses and protective masks during use. In storage should be placed in a dry, cool place, away from the fire source and may cause fire substances.
Last Update：2024-04-10 22:29:15
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CAS: 120075-24-3
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CAS: 120075-24-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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