1206102-10-4
(4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione
CAS: 1206102-10-4
Molecular Formula: C19H19BrN2O4
1206102-10-4 - Names and Identifiers
1206102-10-4 - Physico-chemical Properties
| Molecular Formula | C19H19BrN2O4 |
| Molar Mass | 419.27 |
1206102-10-4 - Upstream Downstream Industry
| Downstream Products | (4R,12aS)-N-(2,4-difluorobenzyl)-7-benzylhydroxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxaMide |
1206102-10-4 - Introduction
Nature:
(4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione is a solid compound that forms white or yellowish crystals. It has a high melting and boiling point and is soluble in some organic solvents such as dichloromethane and ether. It undergoes hydrolysis under alkaline conditions and can form soluble drotervir.
Use:
(4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H, 12AH)-dione is an important organic synthetic intermediate widely used in the field of pharmaceutical synthesis. It plays a key role in the preparation of derotervir, a drug used to treat skin problems such as warts, corns, etc.
Preparation Method:
The preparation of (4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione is usually carried out by organic synthetic chemical methods. The common preparation method includes the reaction of 2-aminopyridine and anisole salt, and the target compound is synthesized by substitution reaction.
Safety Information:
(4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione is safer, but as an organic compound, attention should be paid to its irritation to skin, eyes and respiratory system. When using, wear appropriate personal protective equipment, avoid contact with skin and eyes, and ensure that the operation is carried out in a well-ventilated place. Avoid inhaling dusts or gases of the compound. If taken by mistake or inhaled by mistake, seek medical attention immediately.
Last Update：2024-04-09 19:05:53
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