1208314-89-9
[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]boronic acid
CAS: 1208314-89-9
Molecular Formula: C6H4BClF3NO2
1208314-89-9 - Names and Identifiers
1208314-89-9 - Physico-chemical Properties
| Molecular Formula | C6H4BClF3NO2 |
| Molar Mass | 225.36 |
1208314-89-9 - Introduction
3-Chloro-5-trifluoromethylpyridine-2-boronic acid is an organic compound with the chemical formula C7H4BClF3N. It is a white solid, stable at room temperature. The following is information about the properties, use, preparation and safety of the compound:
Nature:
-Appearance: White solid
-Melting point: about 100-103 degrees Celsius
-Solubility: Soluble in polar organic solvents such as dichloromethane and acetonitrile
-Reactivity: It is a colorless compound, stable in the air. It has a boronic acid group and a chlorotrifluoromethylpyridine group and can be used as a reagent or ligand in organic synthesis reactions.
Use:
-3-Chloro-5-trifluoromethylpyridine-2-boronic acid can be used as a reaction reagent in organic synthesis, for example, as a ligand for copper catalysts in Suzuki-Miyaura reactions.
-It can also be used as a synthetic intermediate for basic ionic liquids (BTFMP), which have important applications in chemical catalysis and separation processes.
Method:
3-Chloro-5-trifluoromethylpyridine-2-boronic acid is usually synthesized by the following steps:
1. 3-chloro-5-trifluoromethylpyridine is reacted with boric acid to obtain 3-chloro-5-trifluoromethylpyridine-2-boronic acid.
Safety Information:
-Detailed safety information for the compound should be obtained from the supplier.
-Correct laboratory procedures should be followed when handling and using this compound.
-It may be a potential hazard to health and the environment, so appropriate safety measures must be followed, such as wearing personal protective equipment, ensuring air ventilation, etc.
Nature:
-Appearance: White solid
-Melting point: about 100-103 degrees Celsius
-Solubility: Soluble in polar organic solvents such as dichloromethane and acetonitrile
-Reactivity: It is a colorless compound, stable in the air. It has a boronic acid group and a chlorotrifluoromethylpyridine group and can be used as a reagent or ligand in organic synthesis reactions.
Use:
-3-Chloro-5-trifluoromethylpyridine-2-boronic acid can be used as a reaction reagent in organic synthesis, for example, as a ligand for copper catalysts in Suzuki-Miyaura reactions.
-It can also be used as a synthetic intermediate for basic ionic liquids (BTFMP), which have important applications in chemical catalysis and separation processes.
Method:
3-Chloro-5-trifluoromethylpyridine-2-boronic acid is usually synthesized by the following steps:
1. 3-chloro-5-trifluoromethylpyridine is reacted with boric acid to obtain 3-chloro-5-trifluoromethylpyridine-2-boronic acid.
Safety Information:
-Detailed safety information for the compound should be obtained from the supplier.
-Correct laboratory procedures should be followed when handling and using this compound.
-It may be a potential hazard to health and the environment, so appropriate safety measures must be followed, such as wearing personal protective equipment, ensuring air ventilation, etc.
Last Update：2024-04-10 22:29:15
