1212406-52-4
(2R,3R)-2-(2-Chloro-phenyl)-1-(2-methoxy-ethyl)-5-oxo-pyrrolidine-3-carboxylic acid
CAS: 1212406-52-4
Molecular Formula: C14H16ClNO4
1212406-52-4 - Names and Identifiers
1212406-52-4 - Physico-chemical Properties
| Molecular Formula | C14H16ClNO4 |
| Molar Mass | 297.73 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD08277075 |
1212406-52-4 - Risk and Safety
| Hazard Class | IRRITANT |
1212406-52-4 - Introduction
(2R,3R)-2-(2-Chloro-phenyl)-1-(2-methoxy-ethyl)-acrylic is an organic compound commonly known by the abbreviation CPPC. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid.
-Molecular formula: C15H17ClNO4.
-Molecular weight: 309.75g/mol.
-Solubility: Soluble in organic solvents such as acetonitrile, methanol and chloroform.
Use:
(2R,3R)-2-(2-chloro-phenyl)-1-(2-methoxy-ethyl)-phenyl acid is a compound used as a pharmaceutical intermediate, mainly used in the synthesis of antibiotics, compound library screening and chemical synthesis.
Preparation Method:
(2R,3R)-2-(2-Chloro-phenyl)-1-(2-methoxy-ethyl)-phenyl acid can be prepared as follows:
First, 2-methoxyethyl borate and benzoyl borate are subjected to a condensation reaction in the presence of sodium hydrogen to obtain a precursor of the target compound.
-Then, the chlorophenyl group is introduced into the precursor through an addition reaction catalyzed by gold cyanide.
-Finally, (2R,3R)-2-(2-chloro-phenyl)-1-(2-methoxy-ethyl)-acid is obtained by acidic hydrolysis.
Safety Information:
- (2R,3R)-2-(2-Chloro-phenyl)-1-(2-methoxy-ethyl)-acid related safety information has not been completely sorted out, so it is necessary to pay attention to the laboratory safety operation specifications before use.
-Because the compound may be toxic to the human body, avoid contact with skin and inhalation of dust, and maintain good ventilation conditions.
-When using this compound, follow appropriate personal protective measures, such as wearing protective gloves, goggles, and laboratory coats.
-When handling or disposing of the compound, local regulations should be followed to ensure a safe environment and correct disposal methods.
Nature:
-Appearance: White crystalline solid.
-Molecular formula: C15H17ClNO4.
-Molecular weight: 309.75g/mol.
-Solubility: Soluble in organic solvents such as acetonitrile, methanol and chloroform.
Use:
(2R,3R)-2-(2-chloro-phenyl)-1-(2-methoxy-ethyl)-phenyl acid is a compound used as a pharmaceutical intermediate, mainly used in the synthesis of antibiotics, compound library screening and chemical synthesis.
Preparation Method:
(2R,3R)-2-(2-Chloro-phenyl)-1-(2-methoxy-ethyl)-phenyl acid can be prepared as follows:
First, 2-methoxyethyl borate and benzoyl borate are subjected to a condensation reaction in the presence of sodium hydrogen to obtain a precursor of the target compound.
-Then, the chlorophenyl group is introduced into the precursor through an addition reaction catalyzed by gold cyanide.
-Finally, (2R,3R)-2-(2-chloro-phenyl)-1-(2-methoxy-ethyl)-acid is obtained by acidic hydrolysis.
Safety Information:
- (2R,3R)-2-(2-Chloro-phenyl)-1-(2-methoxy-ethyl)-acid related safety information has not been completely sorted out, so it is necessary to pay attention to the laboratory safety operation specifications before use.
-Because the compound may be toxic to the human body, avoid contact with skin and inhalation of dust, and maintain good ventilation conditions.
-When using this compound, follow appropriate personal protective measures, such as wearing protective gloves, goggles, and laboratory coats.
-When handling or disposing of the compound, local regulations should be followed to ensure a safe environment and correct disposal methods.
Last Update：2024-04-09 21:04:16
